Constitution of Cerebrospinal Fluid and Blood Database/Specimen in Acute Stage of Subarachnoid Hemorrhage (aSAH) Patients

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01292278
Recruitment Status : Unknown
Verified December 2014 by Karl-Michael Schebesch, University of Regensburg.
Recruitment status was:  Recruiting
First Posted : February 9, 2011
Last Update Posted : December 5, 2014
Technische Universität München
Information provided by (Responsible Party):
Karl-Michael Schebesch, University of Regensburg

Brief Summary:
Neuropeptide Y (NPY) may play a major role in the pathophysiology of aneurysmal subarachnoid hemorrhage (aSAH). To investigate the correlation of NPY in cerebrospinal fluid (CSF) and blood (serum) and the neurological outcome in the acute stage of aSAH.

Condition or disease
Subarachnoid Hemorrhage

Detailed Description:
Evaluation of Neuropeptides in CSF and serum in SAH patients

Study Type : Observational
Estimated Enrollment : 90 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Possible Role of Neuropeptide Y After Spontaneous Subarachnoid Hemorrhage
Study Start Date : January 2006
Estimated Primary Completion Date : August 2015
Estimated Study Completion Date : December 2016

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Bleeding
U.S. FDA Resources

consecutive patients with spontaneous or aneurysmal subarachnoid hemorrhage
control group
no neurological disease but spinal anesthesia

Primary Outcome Measures :
  1. Glasgow Outcome Scale [ Time Frame: 2011-2016 ]

Biospecimen Retention:   Samples Without DNA
cerebrospinal fluid / serum

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Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
consecutive pts. with subarachnoid hemorrhage

Inclusion Criteria:

  • spontaneous or aneurysmal subarachnoid hemorrhage

Exclusion Criteria:

  • age younger than 18 years or older than 70 years
  • inflammatory disease
  • history of former SAH
  • no ventricular drainage

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01292278

Department of Neurosurgery Medical Center University of Regensburg Recruiting
Regensburg, Germany, 93053
Contact: Karl-Michael Schebesch, M.D.    ++49 +941 944 9010   
Principal Investigator: Karl-Michael Schebesch, M.D.         
Sponsors and Collaborators
University of Regensburg
Technische Universität München

Responsible Party: Karl-Michael Schebesch, Karl-Michael Schebesch, MD, University of Regensburg Identifier: NCT01292278     History of Changes
Other Study ID Numbers: CSF 06/179
First Posted: February 9, 2011    Key Record Dates
Last Update Posted: December 5, 2014
Last Verified: December 2014

Keywords provided by Karl-Michael Schebesch, University of Regensburg:
subarachnoid hemorrhage
cerebral vasospasm
neuropeptide Y

Additional relevant MeSH terms:
Subarachnoid Hemorrhage
Pathologic Processes
Intracranial Hemorrhages
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases