A Physician-Based Trial to Increase Colorectal Cancer Screening in Chinese (CRC)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01289288
Recruitment Status : Completed
First Posted : February 3, 2011
Last Update Posted : May 21, 2013
Temple University
National Cancer Institute (NCI)
Information provided by (Responsible Party):
Judy Wang, Georgetown University

Brief Summary:

The objective of this study is to test whether a culturally-tailored in-office based intervention have impact on increasing Chinese physician's recommendation of colorectal cancer (CRC) screening to their nonadherent Chinese patients.

Special aims are to:

  1. Evaluate the efficacy of a culturally-tailored physician intervention on increasing non-adherent Chinese American's patients' CRC screening rate.
  2. Identify factors that mediate or moderate the intervention effects. For example, patients who hold an eastern cultural view or are less acculturated will be more likely to benefit from the intervention than patients who hold a western view or who are more acculturated.

Condition or disease Intervention/treatment Phase
Colorectal Cancer Behavioral: Mailed printed materials and in-office training Phase 1 Phase 2

Detailed Description:
This study is a randomized controlled trial aiming to test the effect of the culturally-tailored in-office based intervention on physicians. A total of 24 Chinese physicians in the Washington DC and Philadelphia areas and a total of 24 eligible Chinese patients from each physician will be recruited for this study. Physicians and their patients are randomized into two groups: A and B. Physician in the intervention group (A) will receive mailed printed materials including a CRC physician guide, patient brochure, flip chart and a poster and two sessions of in-office training aimed to reinforce learning of the topic covered by the mailed materials and provide physicians with hands-on experience in using communication skills with standardized patients. Physicians in the control group (B) will receive nothing until the end of the study. Patients will be followed 12-month later after their completion of the baseline survey and their self-reported CRC screening status will be verified by chart audit.

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 480 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: A Physician-Based Trial to Increase Colorectal Cancer Screening in Chinese
Study Start Date : July 2007
Actual Primary Completion Date : July 2012
Actual Study Completion Date : July 2012

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arm Intervention/treatment
Experimental: Mailed printed materials and in-office training Behavioral: Mailed printed materials and in-office training
  1. Mailed printed materials including CRC physician guide, patient brochure, flip chart and a poster
  2. Two sessions of in-office training with two standardized patients
No Intervention: Control
Usual care

Primary Outcome Measures :
  1. Receipt of CRC screening [ Time Frame: 12 months ]
    Nonadherent Chinese American patient's CRC screening rates.

Information from the National Library of Medicine

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Ages Eligible for Study:   50 Years to 74 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

For Physicians

  1. are Chinese American,
  2. practice primary care,
  3. have a least 75 Chinese patients aged 50 and older in their practice,
  4. can communicate with patients in Chinese (Mandarin, Cantonese, etc.)

For Patients

  1. visiting the participating physician at least once in the past 2 years,
  2. are Chinese Americans,
  3. are 50 years and older,
  4. never had any CRC screening or are overdue for screening.

Exclusion Criteria:

For Patients:

  1. have a colorectal polyp, CRC cancer, or a family history of CRC (first degree relative), and
  2. had updated CRC screening (FOBT within one year, colonoscopy within 10 years, sigmoidoscopy within 5 years and double-contrast barium enema within 5 years).

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01289288

United States, District of Columbia
Georgetown University
Washington DC, District of Columbia, United States, 20007
United States, Pennsylvania
Temple University
Philadelphia, Pennsylvania, United States, 19122
Sponsors and Collaborators
Georgetown University
Temple University
National Cancer Institute (NCI)
Principal Investigator: Judy Wang, Ph.D. Georgetown University

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Judy Wang, Assistant Professor, Georgetown University Identifier: NCT01289288     History of Changes
Other Study ID Numbers: 2007-297
R01CA121023 ( U.S. NIH Grant/Contract )
First Posted: February 3, 2011    Key Record Dates
Last Update Posted: May 21, 2013
Last Verified: May 2013

Keywords provided by Judy Wang, Georgetown University:
colorectal cancer screening
Chinese Americans
patients nonadherent with CRC Screening

Additional relevant MeSH terms:
Colorectal Neoplasms
Intestinal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Digestive System Diseases
Gastrointestinal Diseases
Colonic Diseases
Intestinal Diseases
Rectal Diseases