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Correlation of Arterial Blood Gas (ABG) and Venous Blood Gas (VBG) in the Undifferentiated Critically Ill Patient

This study has been completed.
Information provided by (Responsible Party):
Christiana Care Health Services Identifier:
First received: January 31, 2011
Last updated: November 7, 2012
Last verified: November 2012
The primary objective of this study is to identify a correlation between the pH and pCO2 in arterial and venous blood. The secondary objectives include a correlation of pulse oximetry and arterial pO2 along with subgroup analyses of specific patient populations such as congestive heart failure, chronic obstructive pulmonary disease, diabetic ketoacidosis, pneumonia, overdose, and trauma.

Condition Intervention
Patients Needing Blood Gases
Other: Venous Blood Gas

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Official Title: Correlation of Arterial Blood Gas (ABG) and Venous Blood Gas (VBG) in the Undifferentiated Critically Ill Patient

Further study details as provided by Christiana Care Health Services:

Primary Outcome Measures:
  • Degree to which pH and pCO2 correlate between ABG and VBG [ Time Frame: 5 minutes ]
    ABG and VBG will be obtained 5 minutes apart and compared

Enrollment: 156
Study Start Date: October 2010
Study Completion Date: June 2012
Primary Completion Date: June 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
No Intervention: Venous Blood Gas
All subjects have an ABG and VBG drawn. No intervention.
Other: Venous Blood Gas
patients who have been identified by the treating physician as needing an ABG will receive an VBG is they consent to take part in the study


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Age 18 years or older Signed consent Patient in the ED or ICU Have a disease state that necessitates obtaining an ABG Have a disease state that necessitates pulse oximetry monitoring

Exclusion Criteria:

  • Any contraindication to arterial or venous blood draw Prior enrollment in the study during the current hospitalization Pregnancy Prisoners
  Contacts and Locations
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Please refer to this study by its identifier: NCT01287884

United States, Delaware
Christiana Care Health Services
Newark, Delaware, United States, 19718
Sponsors and Collaborators
Christiana Care Health Services
Principal Investigator: Eli Zeserson, MD Christiana Care Health Services
  More Information

Responsible Party: Christiana Care Health Services Identifier: NCT01287884     History of Changes
Other Study ID Numbers: 600824
Study First Received: January 31, 2011
Last Updated: November 7, 2012

Keywords provided by Christiana Care Health Services:

Additional relevant MeSH terms:
Critical Illness
Disease Attributes
Pathologic Processes processed this record on April 28, 2017