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Evaluation of Filtering Blebs Using the "Wuerzburg Bleb Classification Score" Compared to Other Clinical Findings, e.g. the Intraocular Pressure (IOP)

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ClinicalTrials.gov Identifier: NCT01287442
Recruitment Status : Completed
First Posted : February 1, 2011
Last Update Posted : November 4, 2011
Sponsor:
Information provided by (Responsible Party):
University of Zurich

Brief Summary:

It is well established to assess the functionality of a filtering bleb by intraocular pressure (IOP), either as an absolute value or as a percent reduction, and by the need of additional antiglaucoma drugs. It is also possible to evaluate the appearance of a bleb by a clinical score, e.g. the "Wuerzburg bleb classification score" (WBCS). The purpose of this study was to find out whether there is a correlation between clinical findings, in particular IOP and the WBCS.

100 eyes within two years after trabeculectomy were included into the study. Using colour photographs the filtering bleb was evaluated according to the WBCS from two different examiners, both on different levels of clinical experience. WBCS = 1 indicates poor bleb appearance, WBCS = 15 indicates optimal bleb appearance. At the same time, clinical findings like intraocular pressure, best corrected visual acuity, slit lamp biomicroscopy and medical history were taken by another examiner.

  • Trial with surgical intervention

Condition or disease Intervention/treatment
Glaucoma Procedure: Trabeculectomy

Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Case-Only
Time Perspective: Retrospective
Study Start Date : January 2009
Study Completion Date : December 2010

Resource links provided by the National Library of Medicine



Intervention Details:
  • Procedure: Trabeculectomy
    A scleral flap is created. The aqueous humor is so guided under the conjunctiva to lower IOP.



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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Diagnosis of glaucoma, status post trabeculectomy
Criteria

Inclusion criteria: Diagnosis of glaucoma, status post trabeculectomy

Exclusion criteria: age <18 Jahre, other optic neuropathy than glaucoma


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01287442


Locations
Switzerland
University Hospital Zurich, Ophthalmic Clinic
Zurich, ZH, Switzerland, 8091
Sponsors and Collaborators
University of Zurich
Investigators
Principal Investigator: Jens Funk, Prof. MD University Hospital Zurich, Ophtalmic Clinic

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: University of Zurich
ClinicalTrials.gov Identifier: NCT01287442     History of Changes
Other Study ID Numbers: TE-WBCS-IOP
First Posted: February 1, 2011    Key Record Dates
Last Update Posted: November 4, 2011
Last Verified: November 2011