Try our beta test site
IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...
Trial record 1 of 5 for:    "Renal tubular acidosis"
Previous Study | Return to List | Next Study

Renal Tubular Acidosis in Incident Renal Transplant Recipients

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified January 2011 by Universitaire Ziekenhuizen Leuven.
Recruitment status was:  Recruiting
Information provided by (Responsible Party):
Universitaire Ziekenhuizen Leuven Identifier:
First received: January 25, 2011
Last updated: May 29, 2012
Last verified: January 2011
Metabolic acidosis is a common complication in incident renal transplant recipients. Protracted acidosis may be associated with osteoporosis, inflammation, negative protein balance and malnutrition, and last but not least may cause renal dysfunction. Preliminary data indicate an increased prevalence of nephrocalcinosis in renal transplant biopsies of incident patients presenting with metabolic acidosis. The present study aims (1)evaluate the prevalence and type of renal tubular acidosis (RTA) in incident renal transplant recipients and to identify clinical correlates and (2) to find associations between RTA, nephrolithiasis and nephrocalcinosis

Renal Transplant Disorder

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Renal Tubular Acidosis in Incident Renal Transplant Recipients

Resource links provided by NLM:

Further study details as provided by Universitaire Ziekenhuizen Leuven:

Estimated Enrollment: 50
Study Start Date: May 2012
Estimated Study Completion Date: June 2013
Estimated Primary Completion Date: June 2013 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
renal transplant recipients

Inclusion Criteria:

  • Recipient of a single kidney transplant included in the protocol biopsy program.
  • eGFR > 30 ml/min
  • Age ≥ 18 years
  • Written informed consent

Exclusion Criteria:

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01283880

Contact: Pieter Evenepoel, MD 003216344580

University Hospitals Leuven Recruiting
Leuven, Belgium, 3000
Principal Investigator: Pieter Evenepoel, MD         
Sponsors and Collaborators
Universitaire Ziekenhuizen Leuven
Principal Investigator: Pieter Evenepoel, MD University Hospitals Leuven
  More Information

Responsible Party: Universitaire Ziekenhuizen Leuven Identifier: NCT01283880     History of Changes
Other Study ID Numbers: ML6919
Study First Received: January 25, 2011
Last Updated: May 29, 2012

Keywords provided by Universitaire Ziekenhuizen Leuven:
metabolic acidosis
renal tubular acidosis

Additional relevant MeSH terms:
Acidosis, Renal Tubular
Acid-Base Imbalance
Metabolic Diseases
Renal Tubular Transport, Inborn Errors
Kidney Diseases
Urologic Diseases
Metabolism, Inborn Errors
Genetic Diseases, Inborn processed this record on May 22, 2017