Blood/Interstitial Glucose Measurements and Cognitive Function During Hypoglycemia and Recovery
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|ClinicalTrials.gov Identifier: NCT01283126|
Recruitment Status : Completed
First Posted : January 25, 2011
Last Update Posted : May 9, 2017
|Condition or disease||Intervention/treatment||Phase|
|Hypoglycemia||Procedure: euglycemic and hypoglycemic clamp||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||20 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Blood/Interstitial Glucose Measurements and Cognitive Function During Hypoglycemia and Recovery|
|Actual Study Start Date :||January 2011|
|Actual Primary Completion Date :||October 2014|
|Actual Study Completion Date :||October 2015|
Experimental: Euglycemic and hypoglycemic clamp
Subjects will complete clamp study visit.
Procedure: euglycemic and hypoglycemic clamp
Subjects will undergo standard euglycemic and hypoglycemic clamps, and will have concurrent assessments of cognitive function and measurement of interstitial glucose concentrations.
Other Name: clamp
- cognitive function correlation to blood or interstitial glucose [ Time Frame: 1 year ]This investigator initiated study will evaluate cognitive function at the onset, during and following recovery from hypoglycemia and will determine if cognitive function correlates better with blood or interstitial glucose concentrations.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01283126
|United States, Massachusetts|
|Joslin Diabetes Center|
|Boston, Massachusetts, United States, 02215|
|Principal Investigator:||Howard Wolpert, MD||Joslin Diabetes Center|
|Study Chair:||Greeshma K Shetty, MD||Joslin Diabetes Center|
|Study Chair:||Gail Musen, PhD||Joslin Diabetes Center|
|Study Chair:||Gail Adler, MD, PhD||Brigham and Women's Hospital|