Metabolic Side-effects for Second-generation Antipsychotics
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|ClinicalTrials.gov Identifier: NCT01280396|
Recruitment Status : Unknown
Verified January 2011 by The University of Hong Kong.
Recruitment status was: Recruiting
First Posted : January 20, 2011
Last Update Posted : January 31, 2011
Second-generation antipsychotics (SGAs), including clozapine, are commonly used nowadays as treatment for psychosis. There are increasing concerns about their related metabolic side-effects over weight gain, risks to cause glucose intolerance and hyperlipidemia, and a specific condition known as metabolic syndrome. All these side-effects might be associated with the increased risk of cardiovascular diseases and diabetes mellitus.
This study is to analyze the simple physical measurements (weight and height) and venous blood tests (for fasting blood glucose and lipid) results collected routinely since 2008 (recommended by the local hospital authority as a territory-wide "SGAs Monitoring Program") from those outpatients receiving SGAs (amisulpride, aripiprazole, olanzapine, paliperidone, quetiapine, risperidone and ziprasidone) and/or clozapine, at a local psychiatric outpatient clinic in Hong Kong. The investigators hypothesized that there should be differential risks on metabolic side-effects amongst these SGAs.
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||372 participants|
|Official Title:||Metabolic Side-effects in Patients Receiving Clozapine and Second-generation Antipsychotics in an Outpatient Clinic|
|Study Start Date :||November 2010|
|Estimated Primary Completion Date :||July 2011|
patients receiving SGAs
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01280396
|Contact: Albert Kar Kin Chung, MBBSemail@example.com|
|Western Psychiatric Centre||Recruiting|
|Hong Kong, Hong Kong, 00000|
|Contact: Albert Kar Kin Chung, MBBS +852-22556226 firstname.lastname@example.org|
|Principal Investigator:||Albert Kar Kin Chung, MBBS||Department of Psychiatry, Queen Mary Hospital|