Prognostic Score To Predict Major Complications After Pancreaticoduodenectomy
Pancreaticoduodenectomy (PD) still carries a high rate of severe postoperative complications. No score is currently available to help identify the patient's surgical risk. The purpose of this study was to develop and validate a prognostic score to predict major postoperative complications after PD.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||A PROGNOSTIC SCORE TO PREDICT MAJOR COMPLICATIONS AFTER PANCREATICODUODENECTOMY.|
- Major Complication rate [ Time Frame: Postoperative. Until 30 days after discharge ] [ Designated as safety issue: No ]Clavien-Dindo grade III to V complications considered as major
|Study Start Date:||January 2002|
|Study Completion Date:||October 2010|
|Primary Completion Date:||October 2010 (Final data collection date for primary outcome measure)|
Patients undergoing PD from 2002 to 2010
Resection of pancreatic lesion
The investigators prospectively collected in an electronic database preoperative, intraoperative and outcome data of 700 patients undergoing PD in our Institution from 2002 to 2010. The investigators used a multivariate logistic regression analysis to create a new score to predict severe complications defined as Clavien-Dindo classification III, IV and V. The score was developed using a random two-thirds of the population (469 patients), and was then validated and calibrated in the remaining third of the patients (231).
Please refer to this study by its ClinicalTrials.gov identifier: NCT01278381
|San Raffaele Hospital|
|Milan, Italy, 20132|
|Principal Investigator:||Marco Braga, MD||Università Vita-Salute San Raffaele|