Anticoagulation and Activation - Comparison in Continuous Renal Replacement Therapy
|ClinicalTrials.gov Identifier: NCT01276392|
Recruitment Status : Withdrawn (A main person involved left the site)
First Posted : January 13, 2011
Last Update Posted : August 20, 2015
|Condition or disease|
|Kidney Replacement Disorder|
|Study Type :||Observational|
|Actual Enrollment :||0 participants|
|Official Title:||Platelet Function, Whole Blood Coagulation and Fibrinolysis During Continuous Renal Replacement Therapy - a Comparison of Citrate and Heparin Anticoagulation|
|Study Start Date :||January 2011|
|Estimated Primary Completion Date :||November 2014|
|Estimated Study Completion Date :||February 2015|
10 Patients undergoing continuous renal replacement therapy using heparin for providing anticoagulation. Blood samples taken at 8 predefined timepoints.
10 Patients undergoing continuous renal replacement therapy using citrate for providing anticoagulation. Blood samples taken at 8 predefined timepoints.
- Filter life time of continuous renal replacement therapy [ Time Frame: Individual time point, standardized ]Filter life time measured in hours of duration of continuos renal replacement therapy, filter life time end, when system clotts.
- Activation of coagulation [ Time Frame: beginning of hemodialysis, 1,2,4,12,24,28,72 hours after start of hemodialysis ]blood samples for multiplate, rotem and systemic coagulation paramters
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01276392
|Interdisciplinary Operative Intensive Care Unit, University Hospital Duesseldorf|
|Duesseldorf, NRW, Germany, 40225|
|Principal Investigator:||Detlev Kindgen-Milles, Professor,MD||Department of Anesthesiology, University Hospital Duesseldorf, Heinrich Heine University|