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Ultrasound-image Versus Doppler-guided Radial Artery Cannulation in Infants and Small Children

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified January 2011 by University of Iowa.
Recruitment status was:  Active, not recruiting
Information provided by:
University of Iowa Identifier:
First received: January 11, 2011
Last updated: NA
Last verified: January 2011
History: No changes posted
In infants, percutaneous cannulation of radial artery requires considerable expertise. People have been using Doppler guided radial artery cannulation technique to improve success rate for more than 20 years. Recently, Ultrasound sonography has been utilized for central line placement in pediatrics. The purpose of this study is whether ultrasound guided radial artery cannulation technique improves the success rate compared to traditional doppler guided technique.

Condition Intervention
Patients Requiring Radial Arterial Line Cannulation.
Procedure: Ultrasound
Procedure: Doppler

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment

Resource links provided by NLM:

Further study details as provided by University of Iowa:

Primary Outcome Measures:
  • The primary object is to compare the first attempt success rate between each group. [ Time Frame: 10 minutes ]

Secondary Outcome Measures:
  • As a secondary object, a comparison will be made between groups for overall Success rate within a 10 minute time period. [ Time Frame: 10 minutes ]

Enrollment: 104
Study Start Date: May 2009
Estimated Study Completion Date: December 2011
Estimated Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Ultrasound
Arterial line placed with Ultrasound guidance.
Procedure: Ultrasound
Ultrasound used to place arterial line
Active Comparator: Doppler
Arterial line placed with doppler guidance
Procedure: Doppler
Doppler used to place arterial line


Ages Eligible for Study:   up to 48 Months   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Inclusion criteria

    1. Pediatric patient undergoing scheduled major surgery which require continuous arterial pressure monitoring
    2. Term neonates and children < 4 years old weighing >/= 3 kg and < 12 kg

Exclusion Criteria:

  • Exclusion criteria

    1. Patients with a skin wound or infection around puncture site
    2. Abnormal circulation in the hand (known vascular compromise, mottling, cool skin temp relative to other hand, poor capillary refill)
    3. Recent radial arterial puncture (less than 1 month)
    4. Any emergency surgery or profound hemodynamic instability requiring urgent arterial cannulation.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01276158

United States, Iowa
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States, 52242
Sponsors and Collaborators
University of Iowa
Principal Investigator: Kenichi Ueda, MD University of Iowa
  More Information

Responsible Party: Kenichi Ueda, Department of Anesthesia, University of Iowa Carver College of Medicine Identifier: NCT01276158     History of Changes
Other Study ID Numbers: 200905711 
Study First Received: January 11, 2011
Last Updated: January 11, 2011 processed this record on February 27, 2017