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Effects of Exercise With or Without Blueberries on Cardiovascular Risk Markers

This study has been completed.
Information provided by (Responsible Party):
Fredrik H Nystrom, University Hospital, Linkoeping Identifier:
First received: January 10, 2011
Last updated: July 26, 2012
Last verified: July 2012
About 32 healthy subjects are subjected to 4 weeks of exercise, 4 weeks of washout and 4 weeks of sedentary life style, randomization decides whether they start with exercise or with being "couch potatoes". All participants are also randomized to also consume 150 g of blueberries on exercise days or not. The exercise is constituted of 5 km running 5 days a week during the 4 week period. The exercise period and the "couch" period are started and ended with a 5 km run at maximal speed and the fasting blood samples for cardiovascular risk factors are measured before and after this run, ie 8 times in total.

Condition Intervention
Risk Factors Cardiovascular Disease
Sedentary Life
Biological: Blueberries

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Basic Science
Official Title: Effects of Exercise With or Without Blueberries on Cardiovascular Risk Markers

Resource links provided by NLM:

Further study details as provided by University Hospital, Linkoeping:

Primary Outcome Measures:
  • markers for cardiovascular disease [ Time Frame: 3 months ]
    Insulin levels, glucose levels, lipids, hs-CRP, troponin T

Enrollment: 32
Study Start Date: July 2010
Study Completion Date: March 2011
Primary Completion Date: December 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
No Intervention: conventional food
Regular eating habits during exercise period
Active Comparator: Blueberries
Intervention: Addition of blueberries (150g/day) to regular food during the exercise period on days with exercise
Biological: Blueberries
150 grams of frozen blueberries on the same day as exercise


Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • healthy subjects

Exclusion Criteria:

  • significant disease and disabilities that hinder running
  Contacts and Locations
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Please refer to this study by its identifier: NCT01274078

Linkoeping, Sweden
Sponsors and Collaborators
University Hospital, Linkoeping
  More Information

Responsible Party: Fredrik H Nystrom, MD professor, University Hospital, Linkoeping Identifier: NCT01274078     History of Changes
Other Study ID Numbers: FHN_exc_blueberries
Study First Received: January 10, 2011
Last Updated: July 26, 2012

Keywords provided by University Hospital, Linkoeping:

Additional relevant MeSH terms:
Cardiovascular Diseases
Pathologic Processes processed this record on May 23, 2017