Therapeutic Effects of Cryotherapy on Arthrogenic Muscle Inhibition in Patients With Cruciate Ligament Reconstruction
Recruitment status was: Recruiting
Anterior cruciate ligament(ACL) injury is one of the most common sport injuries. The major problem after ACL reconstruction or rehabilitation program is quadriceps weakness. Previous studies suggested that cryotherapy and transcutaneous electrical nerve stimulation(TENS) can effectively reduce the arthrogenic muscle inhibition caused by experimental swelling.
To exam the effects of 12 weeks cryotherapy and TENS on arthrogenic muscle inhibition in subjects with ACL reconstruction.
Male subjects with isolated ACL injury, age between 18~40 years old are going to receive an ACL reconstruction surgery.
Quadriceps activation level, quadriceps peak torque during maximal voluntary contraction and rate of force development are measure at presurgery, 3-month, 6-month after surgery. After surgery, subjects will receive 12 weeks, 3 days/week, training programs included 20 minutes cryotherapy and exercise training with TENS.
Data will be analyzed using SPSS 13.0 software (SPSS Inc., Chicago, IL). One-way ANOVA will be used to analysis data.
|Study Design:||Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Therapeutic Effects of Cryotherapy and Transcutaneous Nerves Stimulation on Arthrogenic Muscle Inhibition in Patients With Anterior Cruciate Ligament Reconstruction|
- Muscle activation [ Time Frame: 6 months ] [ Designated as safety issue: Yes ]To provide information of individual muscles for the correlation analyses, parameters of muscle activation, such as the integrated electromyography (EMG) normalized to the maximal M wave, are favored.
|Study Start Date:||January 2011|
|Estimated Study Completion Date:||December 2014|
|Estimated Primary Completion Date:||September 2014 (Final data collection date for primary outcome measure)|
Experimental: ice, rate of force development
to monitor the long term effect of cryotherapy in rate of force development.
cryotherapy is given with other physical training
- Skin preparation and EMG setting.
- Fill out knee joint function questionnaire.
- Warmup with a stationary bike.
- Single hop for distance.
- MVIC test and EMG recording.
- Endurance test.
- Record surface EMG of vastus lateralis, vastus medialis, biceps femoris and semitendinosus during maximal voluntary contraction.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01273649
|National Taiwan University|
|Taipei, Taiwan, 100|
|Principal Investigator:||HK Wang, PhD||National Taiwan University Hospital|