Evaluation of Sloan-Charts for Assessment of Disease Progress in Multiple Sclerosis
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|ClinicalTrials.gov Identifier: NCT01272596|
Recruitment Status : Completed
First Posted : January 10, 2011
Last Update Posted : December 22, 2017
Impairment of visual deficits, in particular contrast acuity and contrast impairment are frequent symptoms in MS. However, visual function is not appropriately covered by the standard tools for clinical assessment, namely, the EDSS and the MSFC.
The primary aim of this study is to investigate, whether in MS patients contrast acuity and sensitivity change over a period of two years.
Secondary aims are the correlation of visual contrast parameters with structural retinal changes and quality of life.
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||100 participants|
|Official Title:||Evaluation of Low Contrast Sloan Visual Charts as Method for the Assessment of Disease Progression in Multiple Sclerosis|
|Study Start Date :||December 2009|
|Actual Primary Completion Date :||November 2013|
|Actual Study Completion Date :||November 2013|
Multiple Sclerosis Patients
Patients with Clinically Isolated Syndrome or definite Multiple Sclerosis (either relapsing-remitting or secondary progressive)
- Visual Contrast Acuity [ Time Frame: 24 Months ]
- Structural and Functional Changes of Optic Pathway [ Time Frame: 24 Months ]
- Clinical Neurological Assessment [ Time Frame: 24 Months ]
- Quality of Life [ Time Frame: 24 Months ]
- Contrast Sensitivity [ Time Frame: 24 Months ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01272596
|NeuroCure Clinical Reserach Center, Charité Universitaetsmedizin|
|Berlin, Germany, 10117|
|Principal Investigator:||Jan M Dörr, MD||NeuroCure Clinical Research Center, Charité Universitaetsmedizin Berlin|