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Glucose, Whey Protein and Time to the Next Meal on Mealtime Food Intake in Children

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ClinicalTrials.gov Identifier: NCT01272427
Recruitment Status : Completed
First Posted : January 7, 2011
Last Update Posted : February 15, 2013
Sponsor:
Collaborator:
Canadian Institutes of Health Research (CIHR)
Information provided by (Responsible Party):
G. Harvey Anderson, University of Toronto

Brief Summary:
The investigators hypothesize that glucose and whey protein given 30 and 60 min before a pizza meal will exert different effects on food intake in adolescent children, and will depend on pubertal stage. Food intake will be measured at 30 and 60 min following a glucose(0.75 g of glucose/kg body weight), whey protein (0.75 g of glucose/kg body weight) or sweetened noncaloric beverage. Subjective appetite will be measured as well.

Condition or disease Intervention/treatment Phase
Obesity Dietary Supplement: water with glucose Dietary Supplement: water and whey protein Dietary Supplement: water with noncaloric sweetener Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 36 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single (Participant)
Primary Purpose: Prevention
Official Title: The Effect of Glucose, Whey Protein and Time to the Next Meal on Food Intake and Subjective Appetite in Normal Weight and Overweight/Obese Children
Study Start Date : January 2010
Actual Primary Completion Date : December 2012
Actual Study Completion Date : February 2013

Resource links provided by the National Library of Medicine

Drug Information available for: Dextrose
U.S. FDA Resources

Arm Intervention/treatment
Experimental: noncaloric beverage
noncaloric sweetened beverage administered 30 min prior to mealtime
Dietary Supplement: water with noncaloric sweetener
0.15 g of sucralose added to water
Experimental: noncaloric beverage (60 min)
noncaloric sweetened beverage administered 60 min prior to mealtime
Dietary Supplement: water with noncaloric sweetener
0.15 g of sucralose added to water
Experimental: glucose beverage
glucose beverage administered 30 min prior to mealtime
Dietary Supplement: water with glucose
0.75 g/kg body weight of glucose added to water
Experimental: glucose beverage (60 min)
glucose beverage administered 60 min prior to mealtime
Dietary Supplement: water with glucose
0.75 g/kg body weight of glucose added to water
Experimental: whey protein beverage
whey protein beverage administered 30 min prior to mealtime
Dietary Supplement: water and whey protein
0.75 g/kg body weight of whey protein added to water
Experimental: whey protein beverage (60 min)
whey protein beverage administered 60 min prior to mealtime
Dietary Supplement: water and whey protein
0.75 g/kg body weight of whey protein added to water



Primary Outcome Measures :
  1. Food intake (kcal) [ Time Frame: 30 and 60 min after the treatment ]

Secondary Outcome Measures :
  1. subjective appetite [ Time Frame: 0-120 min ]


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Ages Eligible for Study:   9 Years to 14 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • children with no emotional, behavioral or learning problems

Exclusion Criteria:

  • underweight children
  • children with emotional, behavioral or learning problems
  • children who dislike foods in study

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01272427


Locations
Canada, Ontario
Department of Nutritional Sciences
Toronto, Ontario, Canada, M5S 3E2
Sponsors and Collaborators
University of Toronto
Canadian Institutes of Health Research (CIHR)
Investigators
Principal Investigator: Harvey Anderson, PhD University of Toronto

Responsible Party: G. Harvey Anderson, Professor, University of Toronto
ClinicalTrials.gov Identifier: NCT01272427     History of Changes
Other Study ID Numbers: FoodIntakeKids_21595
First Posted: January 7, 2011    Key Record Dates
Last Update Posted: February 15, 2013
Last Verified: February 2013