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Red Cell Distribution Width and Mortality in Adult Pneumonia Patients

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified December 2010 by Rambam Health Care Campus.
Recruitment status was:  Not yet recruiting
Information provided by:
Rambam Health Care Campus Identifier:
First received: January 5, 2011
Last updated: NA
Last verified: December 2010
History: No changes posted

Abstract Pneumonia is a leading cause of severe morbidity and mortality among adults. During the last two decades, several scores were developed to evaluate the probability of morbidity and mortality among patients with community acquired pneumonia (CAP), such as the PORT score and the CURB65. Recently, several studies showed that elevated Red Cell Distribution Width (RDW) could be used as a prognostic tool for predicting severe morbidity and mortality among patients with cardiac diseases.

RDW is a quantitative measure for red blood cell (RBC) size variability. Recent studies have suggested that high levels of RDW are in association with higher mortality among cardiovascular patients.

RDW has not yet been studied as a prognostic sign in CAP. The goal of this study is to examine the role of RDW as a prognostic factor for severe morbidity and mortality among patients who were hospitalized with CAP , independently to Hemoglobin levels, renal function and inflammatory markers.


Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Retrospective

Resource links provided by NLM:

Further study details as provided by Rambam Health Care Campus:

Estimated Enrollment: 2000
Study Start Date: January 2011

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Adult patients with pneumonia

Inclusion Criteria:

patients 18 years and older, hospitalized due to pneumonia between 2005-2010. All patients must have RDW values.

Exclusion Criteria:

  • under 18 no RDW value The primary cause of hospitalization was not pneumonia
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  More Information

Responsible Party: Eyal Braun, MD, Rambam Health Care Campus Identifier: NCT01271205     History of Changes
Other Study ID Numbers: 580CTIL
Study First Received: January 5, 2011
Last Updated: January 5, 2011

Keywords provided by Rambam Health Care Campus:
prognostic factor

Additional relevant MeSH terms:
Lung Diseases
Respiratory Tract Diseases
Respiratory Tract Infections processed this record on May 25, 2017