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Red Cell Distribution Width and Mortality in Adult Pneumonia Patients

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ClinicalTrials.gov Identifier: NCT01271205
Recruitment Status : Unknown
Verified December 2010 by Rambam Health Care Campus.
Recruitment status was:  Not yet recruiting
First Posted : January 6, 2011
Last Update Posted : January 6, 2011
Sponsor:
Information provided by:
Rambam Health Care Campus

Brief Summary:

Abstract Pneumonia is a leading cause of severe morbidity and mortality among adults. During the last two decades, several scores were developed to evaluate the probability of morbidity and mortality among patients with community acquired pneumonia (CAP), such as the PORT score and the CURB65. Recently, several studies showed that elevated Red Cell Distribution Width (RDW) could be used as a prognostic tool for predicting severe morbidity and mortality among patients with cardiac diseases.

RDW is a quantitative measure for red blood cell (RBC) size variability. Recent studies have suggested that high levels of RDW are in association with higher mortality among cardiovascular patients.

RDW has not yet been studied as a prognostic sign in CAP. The goal of this study is to examine the role of RDW as a prognostic factor for severe morbidity and mortality among patients who were hospitalized with CAP , independently to Hemoglobin levels, renal function and inflammatory markers.


Condition or disease
Pneumonia

Study Type : Observational
Estimated Enrollment : 2000 participants
Observational Model: Case-Only
Time Perspective: Retrospective
Study Start Date : January 2011

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Pneumonia
U.S. FDA Resources





Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Adult patients with pneumonia
Criteria

Inclusion Criteria:

patients 18 years and older, hospitalized due to pneumonia between 2005-2010. All patients must have RDW values.

Exclusion Criteria:

  • under 18 no RDW value The primary cause of hospitalization was not pneumonia

Responsible Party: Eyal Braun, MD, Rambam Health Care Campus
ClinicalTrials.gov Identifier: NCT01271205     History of Changes
Other Study ID Numbers: 580CTIL
First Posted: January 6, 2011    Key Record Dates
Last Update Posted: January 6, 2011
Last Verified: December 2010

Keywords provided by Rambam Health Care Campus:
pneumonia
RDW
mortality
prognostic factor

Additional relevant MeSH terms:
Pneumonia
Lung Diseases
Respiratory Tract Diseases
Respiratory Tract Infections