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Treatment of Conduct Problems and Depression

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01267773
Recruitment Status : Unknown
Verified March 2013 by Jennifer Wolff, Rhode Island Hospital.
Recruitment status was:  Recruiting
First Posted : December 29, 2010
Last Update Posted : March 21, 2013
Brown University
Information provided by (Responsible Party):
Jennifer Wolff, Rhode Island Hospital

Brief Summary:
Having both depression and conduct problems at the same time has been found to be associated with increased risk for the other and increased risk of negative outcomes. This study will develop an family based cognitive behavioral treatment protocol for youths with both conduct problems and depression, that will take be administered over the course of six months. Youth with comorbid conduct problems and depression will be assigned to the experimental condition or treatment as usual in a community care setting. The treatment manual will be revised as needed. Youth will be assessed before and after treatment to examine program potential. The goal of this research is to develop a more comprehensive outpatient treatment for youth with both conduct problems and depression.

Condition or disease Intervention/treatment Phase
Depression Oppositional Defiant Disorder Conduct Disorder Behavioral: Integrated Treatment Phase 1

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 30 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Treatment of Youth Comorbid Conduct Problems and Depression
Study Start Date : August 2010
Estimated Primary Completion Date : May 2013
Estimated Study Completion Date : May 2013

Resource links provided by the National Library of Medicine

Arm Intervention/treatment
Active Comparator: Sequential Treatment Behavioral: Integrated Treatment
Experimental: Integrated Treatment Behavioral: Integrated Treatment

Primary Outcome Measures :
  1. Depression Symptoms [ Time Frame: baseline to week 24 ]
    Change in depression symptoms from baseline to week 24 will be measured using the Children's Depression Inventory

  2. oppositional symptoms [ Time Frame: baseline to week 24 ]
    change in symptoms of oppositionality from baseline to week 24 will be measured using the Disruptive Behavior Disorders Scale

Information from the National Library of Medicine

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Ages Eligible for Study:   8 Years to 14 Years   (Child)
Sexes Eligible for Study:   All

Inclusion Criteria:

  • 8-14 years old
  • Diagnosis of ODD or CD
  • Diagnosis of Depression
  • Speaks English

Exclusion Criteria:

  • Developmental/cognitive delays
  • Substance dependence
  • Psychotic disorder or symptoms

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01267773

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Contact: Jennifer C Wolff, PhD 4014443790

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United States, Rhode Island
Rhode Island Hospital Recruiting
Providence, Rhode Island, United States, 02903
Contact: Jennifer C Wolff, PhD    401-444-3790   
Sponsors and Collaborators
Rhode Island Hospital
Brown University
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Principal Investigator: Jennifer C Wolff, PhD Rhode Island Hospital/Brown University
Principal Investigator: Anthony Spirito, PhD Brown University

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Responsible Party: Jennifer Wolff, Staff Psychologist, Rhode Island Hospital Identifier: NCT01267773     History of Changes
Other Study ID Numbers: MH086606
First Posted: December 29, 2010    Key Record Dates
Last Update Posted: March 21, 2013
Last Verified: March 2013

Keywords provided by Jennifer Wolff, Rhode Island Hospital:
conduct problems

Additional relevant MeSH terms:
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Depressive Disorder
Conduct Disorder
Attention Deficit and Disruptive Behavior Disorders
Pathologic Processes
Behavioral Symptoms
Mood Disorders
Mental Disorders
Neurodevelopmental Disorders