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Measuring Cardiovascular Stress in Patients on Hemodialysis

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified December 2010 by West Penn Allegheny Health System.
Recruitment status was:  Enrolling by invitation
Information provided by:
West Penn Allegheny Health System Identifier:
First received: December 23, 2010
Last updated: December 27, 2010
Last verified: December 2010
To determine if proprietary software that uses pulse-wave analysis to interpret the output of a conventional pulse-oximeter, can predict the onset of circulatory stress, before changes in blood pressure and pulse occur, in patients undergoing outpatient hemodialysis.

Circulatory Stress

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Measuring Cardiovascular Stress in Patients on Hemodialysis

Resource links provided by NLM:

Further study details as provided by West Penn Allegheny Health System:

Primary Outcome Measures:
  • photoplethysmography [ Time Frame: 5 hours ]
    Pulse-wave analysis of an oximeter signal

Secondary Outcome Measures:
  • blood pressure [ Time Frame: 5 hours ]
    measured continuously during treatment

Estimated Enrollment: 60
Study Start Date: November 2010
Estimated Study Completion Date: November 2011
Estimated Primary Completion Date: November 2011 (Final data collection date for primary outcome measure)
chronic hemodialysis outpatients


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Outpatients receiving hemodialysis at a single center

Inclusion Criteria:

  • Patients having regular outpatient dialysis treatments
  • Patients who are willing and able to provide informed consent

Exclusion Criteria:

  • Patients who do not wish to participate
  • Patients with contraindications to attachment of monitoring devices
  • Patients with skin rash or hypersensitivity to the adhesive sensors
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Please refer to this study by its identifier: NCT01267617

United States, Pennsylvania
Allegheny General Hospital
Pittsburgh, Pennsylvania, United States, 15212
Sponsors and Collaborators
West Penn Allegheny Health System
Principal Investigator: Rita L McGill, MD West Penn Allegheny Health System
  More Information

Responsible Party: Rita L. McGill MD, West Penn Allegheny Health System Identifier: NCT01267617     History of Changes
Other Study ID Numbers: RC-5046
Study First Received: December 23, 2010
Last Updated: December 27, 2010

Keywords provided by West Penn Allegheny Health System:
circulatory stress

Additional relevant MeSH terms:
Vascular Diseases
Cardiovascular Diseases processed this record on April 28, 2017