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The Value of the Trendelenburg Position During Routine Colonoscopy: A Pilot Study.

This study has been completed.
Information provided by (Responsible Party):
University of Missouri-Columbia Identifier:
First received: December 23, 2010
Last updated: August 4, 2016
Last verified: August 2016
Colonoscopy is a procedure commonly performed to screen for colon cancer and to look for and remove colon polyps. It involves inserting a flexible tube, equipped with a video-camera at the tip, through the colon. The insertion process can be difficult in some patients, resulting in an uncomfortable and lengthy procedure. Colonoscopy procedures are typically started with the patient positioned on their left side. If there is later difficulty advancing the colonoscope, the patient is shifted to other positions (e.g. back, right side, prone). We postulate that raising the foot of the bed so that the stretcher forms a 15 degrees angle with the floor ("Trendelenburg position") may make the colonoscopy easier and more comfortable to the patient. This is a position commonly used in gynecologic surgery. This is a pilot project for us to gain experience with doing colonoscopy this way. The enrolled patient will be assigned randomly to 2 groups: one in the standard left lateral position and one in the 15 degree Trendelenberg position. We will be collecting data regarding the procedure from each group in the form of questionnaire and data sheet which will be filled during or at the conclusion of the procedure.

Condition Intervention
Procedure: Trendelenburg position
Procedure: Standard care

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Screening
Official Title: The Value of the Trendelenburg Position During Routine Colonoscopy: A Pilot Study.

Resource links provided by NLM:

Further study details as provided by University of Missouri-Columbia:

Primary Outcome Measures:
  • The time of the procedure from the insertion of the colonoscope until the cecal base is reached [ Time Frame: This outcome is measured when the cecum is intubated during a colonoscopy ] [ Designated as safety issue: No ]

Enrollment: 66
Study Start Date: January 2011
Study Completion Date: February 2012
Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Trendelenburg position
The endoscopist places the patient in 15° Trendelenberg position immediately prior to the initiation of the colonoscopy.
Procedure: Trendelenburg position
The patient will be placed in the Trendelenburg position with a 15 degree angle of inclination
Other Name: Head-Down Tilt
Standard care
The patient will have colonoscopy in the standard horizontal position
Procedure: Standard care
The patient will be placed in the standard horizontal position


Ages Eligible for Study:   18 Years to 75 Years   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Patient age between 18-75 years old.
  • Colonoscopy performed for polyp surveillance or colon cancer screening purposes.
  • Patient able to provide informed consent.

Exclusion Criteria:

  • History of colon resection
  • History of inflammatory bowel disease
  • Pregnancy
  • History of ischemic optic neuropathy or glaucoma
  • Patient unable to provide informed consent
  • Patients who did not fast for ≥2 hours prior to presenting for the procedure
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Please refer to this study by its identifier: NCT01267123

Sponsors and Collaborators
University of Missouri-Columbia
Principal Investigator: Abdo M Saad, MD University of Missouri-Columbia
  More Information

Responsible Party: University of Missouri-Columbia Identifier: NCT01267123     History of Changes
Other Study ID Numbers: 1173017 
Study First Received: December 23, 2010
Last Updated: August 4, 2016
Health Authority: United States: Institutional Review Board processed this record on September 29, 2016