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Computerized Neuropsychology in Idiopathic Normal Pressure Hydrocephalus (INPH)

This study has been completed.
Sponsor:
Information provided by:
Umeå University
ClinicalTrials.gov Identifier:
NCT01265251
First received: December 21, 2010
Last updated: December 22, 2010
Last verified: December 2010
  Purpose
A computerised neuropsychological test battery to be used as a standardised tool assessing the cognitive domains affected by idiopathic normal pressure hydrocephalus INPH was developed. The aim of this study is to investigate the reliability, validity and feasibility of the battery.

Condition Intervention
Normal Pressure Hydrocephalus Device: Computerized neuropsychological test Other: Conventional neuropsychological test

Study Type: Observational
Study Design: Time Perspective: Cross-Sectional
Official Title: Evaluation of a Computerised Neuropsychological Test Battery for Idiopathic Normal Pressure Hydrocephalus (INPH)

Resource links provided by NLM:


Further study details as provided by Umeå University:

Primary Outcome Measures:
  • Validity [ Time Frame: Within 24 h ]
    Computerized test battery and equivalent standard neuropsychological test battery is given to the same subject. Correlation between paper and pen and equivalent computerized test is calculated as a validity measure.

  • Reliability [ Time Frame: More than 7 days, within 2 months ]
    The computerized test battery is given to the same subject twice. Correlation between the two tests is calculated as a test-retest reliability measure.

  • Feasibility [ Time Frame: Within 24 h ]
    Patients under the investigation for INPH are given the computerized test battery. Number of patients who manage to complete the test is the feasibility measure.


Enrollment: 97
Study Start Date: August 2007
Study Completion Date: April 2010
Primary Completion Date: April 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Test-retest
Forty-four healthy elderly 60-82 years old
Device: Computerized neuropsychological test
Computerized neuropsychological test battery.
Validity
Twenty six patients with various diseases and various ages
Device: Computerized neuropsychological test
Computerized neuropsychological test battery.
Other: Conventional neuropsychological test
Conventional neuropsychological test (paper and pen)
Feasibility
Twenty seven patients under the preoperative investigation for INPH
Device: Computerized neuropsychological test
Computerized neuropsychological test battery.

  Eligibility

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Reliability: Healthy elderly Validity: Various diseases Feasibility: Possible INPH-patients
Criteria

Inclusion Criteria:

  • Probable INPH under investigation
  • Healthy elderly
  • Various diseases

Exclusion Criteria:

  • (Healthy elderly) medications affecting nervous system
  • (Healthy elderly)heart disease
  • (Healthy elderly)diabetes
  • (Healthy elderly)disease of the nervous system
  • (Healthy elderly)MMSE < 28
  • (Healthy elderly)vascular risk factors (Two of: 1 hypertension, 2 smoking or 3 hyperlipidemia)
  • (Healthy elderly)serious disease that may shorten life expectancy
  • (Various diseases) Affected motor functions
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01265251

Locations
Sweden
Department of Clinical Neuroscience
Umeå, Västerbotten, Sweden, SE-901 85
Sponsors and Collaborators
Umeå University
Investigators
Principal Investigator: Anders Behrens, M.D., M.Sc. Department of Clinical Neuroscience
  More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Anders Behrens M.D., Department of Clinical Neuroscience
ClinicalTrials.gov Identifier: NCT01265251     History of Changes
Other Study ID Numbers: 07-088M
Study First Received: December 21, 2010
Last Updated: December 22, 2010

Keywords provided by Umeå University:
Normal Pressure Hydrocephalus
Neuropsychological Test
Assessment of cognitive disorders/dementia
Neuropsychological assessment

Additional relevant MeSH terms:
Hydrocephalus
Hydrocephalus, Normal Pressure
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases

ClinicalTrials.gov processed this record on June 27, 2017