Working… Menu

Computerized Neuropsychology in Idiopathic Normal Pressure Hydrocephalus (INPH)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01265251
Recruitment Status : Completed
First Posted : December 23, 2010
Last Update Posted : December 23, 2010
Information provided by:
Umeå University

Brief Summary:
A computerised neuropsychological test battery to be used as a standardised tool assessing the cognitive domains affected by idiopathic normal pressure hydrocephalus INPH was developed. The aim of this study is to investigate the reliability, validity and feasibility of the battery.

Condition or disease Intervention/treatment
Normal Pressure Hydrocephalus Device: Computerized neuropsychological test Other: Conventional neuropsychological test

Layout table for study information
Study Type : Observational
Actual Enrollment : 97 participants
Time Perspective: Cross-Sectional
Official Title: Evaluation of a Computerised Neuropsychological Test Battery for Idiopathic Normal Pressure Hydrocephalus (INPH)
Study Start Date : August 2007
Actual Primary Completion Date : April 2010
Actual Study Completion Date : April 2010

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Hydrocephalus

Group/Cohort Intervention/treatment
Forty-four healthy elderly 60-82 years old
Device: Computerized neuropsychological test
Computerized neuropsychological test battery.

Twenty six patients with various diseases and various ages
Device: Computerized neuropsychological test
Computerized neuropsychological test battery.

Other: Conventional neuropsychological test
Conventional neuropsychological test (paper and pen)

Twenty seven patients under the preoperative investigation for INPH
Device: Computerized neuropsychological test
Computerized neuropsychological test battery.

Primary Outcome Measures :
  1. Validity [ Time Frame: Within 24 h ]
    Computerized test battery and equivalent standard neuropsychological test battery is given to the same subject. Correlation between paper and pen and equivalent computerized test is calculated as a validity measure.

  2. Reliability [ Time Frame: More than 7 days, within 2 months ]
    The computerized test battery is given to the same subject twice. Correlation between the two tests is calculated as a test-retest reliability measure.

  3. Feasibility [ Time Frame: Within 24 h ]
    Patients under the investigation for INPH are given the computerized test battery. Number of patients who manage to complete the test is the feasibility measure.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Reliability: Healthy elderly Validity: Various diseases Feasibility: Possible INPH-patients

Inclusion Criteria:

  • Probable INPH under investigation
  • Healthy elderly
  • Various diseases

Exclusion Criteria:

  • (Healthy elderly) medications affecting nervous system
  • (Healthy elderly)heart disease
  • (Healthy elderly)diabetes
  • (Healthy elderly)disease of the nervous system
  • (Healthy elderly)MMSE < 28
  • (Healthy elderly)vascular risk factors (Two of: 1 hypertension, 2 smoking or 3 hyperlipidemia)
  • (Healthy elderly)serious disease that may shorten life expectancy
  • (Various diseases) Affected motor functions

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01265251

Layout table for location information
Department of Clinical Neuroscience
Umeå, Västerbotten, Sweden, SE-901 85
Sponsors and Collaborators
Umeå University
Layout table for investigator information
Principal Investigator: Anders Behrens, M.D., M.Sc. Department of Clinical Neuroscience
Publications automatically indexed to this study by Identifier (NCT Number):
Layout table for additonal information
Responsible Party: Anders Behrens M.D., Department of Clinical Neuroscience Identifier: NCT01265251    
Other Study ID Numbers: 07-088M
First Posted: December 23, 2010    Key Record Dates
Last Update Posted: December 23, 2010
Last Verified: December 2010
Keywords provided by Umeå University:
Normal Pressure Hydrocephalus
Neuropsychological Test
Assessment of cognitive disorders/dementia
Neuropsychological assessment
Additional relevant MeSH terms:
Layout table for MeSH terms
Hydrocephalus, Normal Pressure
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases