Imaging Cerebral and Sub-cerebral Correlates of Meditative States (calm)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified December 2010 by Boston University.
Recruitment status was  Recruiting
Emory University
Information provided by:
Boston University Identifier:
First received: December 16, 2010
Last updated: NA
Last verified: December 2010
History: No changes posted
Three groups of subjects are trained to practice mindfulness meditation, compassion meditation, or attend a health training control class. Individuals from each group will undergo structural and functional brain imaging before and after training. The hypothesis is that the compassion meditation group will show the largest changes in brain structure and function. In a second series of experiments, the subjects practicing a Tibetan meditation practice will be undergo MRI thermometry imaging to construct detailed three dimensional temperature maps of their bodies before, during, and after they perform this practice.


Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Imaging Cerebral and Sub-cerebral Correlates of Meditative States

Resource links provided by NLM:

Further study details as provided by Boston University:

Estimated Enrollment: 58
Study Start Date: January 2010
Estimated Study Completion Date: October 2011
Estimated Primary Completion Date: October 2011 (Final data collection date for primary outcome measure)
HealthEd receives training health education. Mindfulness receives training in mindfulness meditation. Compassion receives training in compassion meditation.

Detailed Description:
Structural (MRI) Imaging will be used to measure changes in cortical thickness in the pre and post training groups. Function (fMRI) Imaging will be used to measure changes in cortical and sub-cortical responses to a series of affectively controlled visual images, presented during scanning. MRI Thermometry Imaging will be used to construct three dimensional temperature maps of subjects while performing meditation in the scanner.

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Community Sample

Inclusion Criteria:

  • Age 18-65 for the mindfulness-compassion study
  • Prior training in gtummo meditation for the gtummo study

Exclusion Criteria:

  • Previous experience with meditation for the mindfulness-compassion study
  Contacts and Locations
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Please refer to this study by its identifier: NCT01262404

Contact: Terri Sivilli, AB 404 778 2256

United States, Massachusetts
Boston University Dept. of Cognitive and Neural Systems Recruiting
Boston, Massachusetts, United States, 02215
Principal Investigator: Eric L Schwartz, PhD         
Sponsors and Collaborators
Boston University
Emory University
Principal Investigator: Eric L Schwartz, PhD Boston University
  More Information

No publications provided

Responsible Party: Professor Eric L. Schwartz, Boston University Identifier: NCT01262404     History of Changes
Other Study ID Numbers: BU-Emory-01, AT005728-01
Study First Received: December 16, 2010
Last Updated: December 16, 2010
Health Authority: United States: Psychiatry Dept. DSMB, Emory University processed this record on November 27, 2015