Steady State Vestibular Evoked Myogenic Potentials

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01260077
Recruitment Status : Completed
First Posted : December 15, 2010
Last Update Posted : December 15, 2010
Information provided by:
Universidade Estadual de Ciências da Saúde de Alagoas

Brief Summary:
Objective: At present, vestibular evoked myogenic potentials are analyzed only in the time domain. A technique to evaluate this potential in the frequency domain could provide more information, but has only been applied within the last year. Design and Study Sample: In this study we recorded vestibular evoked myogenic potential in the time domain, in 156 ears of 78 normal-hearing young adults, at frequencies of 250, 500, 1000 and 2000 Hz, with intensity of 90 dB nHL. Next, the steady state vestibular evoked myogenic potential was recorded at the same carrying frequencies, modulated at 20, 37, 40, 43, 70, 77 and 80 Hz. Results: The responses found by modulated frequency, regardless of carrier, recorded a higher presence of peaks and mean amplitudes between 20 and 70 Hz, especially at 40 Hz. Conclusions: The results show that the observation technique in the frequency domain is feasible and shows a strong association with the time domain for recording vestibular evoked myogenic potentials, at carrying frequencies of 250, 500, 1000 or 2000 Hz.

Condition or disease
Normal Vestibular Evoked Potentials in Frequency Domain

Study Type : Observational
Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Steady State Vestibular Evoked Myogenic Potentials

Experimental group
The sample was composed of 78 individuals (156 ears), 40 females (80 ears) and 38 males (76 ears).

Primary Outcome Measures :
  1. A technique to evaluate vestibular evoked myogenic potential in the frequency domain

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Ages Eligible for Study:   18 Years to 35 Years   (Adult)
Sexes Eligible for Study:   All
Sampling Method:   Probability Sample
Study Population
Normal subjects.

Inclusion criteria: age between 18 and 35 years and auditory threshold less than or equal to 20 dBHL, between 0.5 and 8 kHz, with inter-ear frequency difference less than or equal to 10 dB.

Exclusion criteria were: exposure to occupational or leisure noise; otological surgery; more than three ear infections within the last year; use of ototoxic medication; buzzing in the ear, vertigo, dizziness or other cochlear-vestibular symptoms ; presence of systemic alterations that could contribute to cochlear-vestibular pathologies, such as diabetes, hypertension, dyslipidemias and/or hormonal alterations.

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: PhD Pedro de Lemos Menezes, Professor, UNCISAL Identifier: NCT01260077     History of Changes
Other Study ID Numbers: CEP_UNCISAL_1010/2009
First Posted: December 15, 2010    Key Record Dates
Last Update Posted: December 15, 2010
Last Verified: February 2009