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Influence of Direction of Movement While Walking

This study has been completed.
Information provided by:
Medical University of Silesia Identifier:
First received: November 29, 2010
Last updated: December 6, 2010
Last verified: November 2010
The aim of the study is evaluation of cerebral blood flow (based on testing the rate of flow in middle cerebral arteries by transcranial Doppler ultrasound) during different forms of walking training - walk forwards and backwards, with closed and open eyes.

Changes in Blood Flow to the Brain Changes Depending on the Form of Walking

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Influence of Direction of Movement While Walking Upon the Blood Flow Rate Through Brain, Examined by Transcranial Doppler Sonography in Young Healthy Subjects.

Further study details as provided by Medical University of Silesia:

Primary Outcome Measures:
  • Transcranial Doppler sonography in young healthy subjects. [ Time Frame: 5 months ]
    Significant changes in blood flow to the brain depending on the form of walking and its conditions were observed. Changes in the right middle cerebral artery were more diverse than in the left artery. Difficulty in walking training forms gave long-term vasodilation.

Enrollment: 1
Study Start Date: December 2008
Study Completion Date: April 2009
Primary Completion Date: January 2009 (Final data collection date for primary outcome measure)
examining group
20 healthy subjects (11 men, 9 women, average age 23.94)
control group
6 healthy subjects (3 men, 3 women, average age 23.6)

Detailed Description:
In the third minute of training walking a significant increase in blood flow velocity was recorded, both in right and left middle cerebral arteries. It was observed in the left artery during all forms of training. In the right artery it occurred only during three forms of difficult training, and was preceded by significant decrease in blood flow in the first minute of the gait with eyes closed. The output values of the rate of blood flow in both right and left middle cerebral arteries became progressively reduced in the successive stages of gait. Pressure and pulse rates did not correlate with the variables of blood flow velocity in middle cerebral arteries.

Ages Eligible for Study:   20 Years to 24 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
20 healthy subjects (11 men, 9 women, average age 23.94) participated in a study measuring the speed of blood flow in middle cerebral arteries using transcranial Doppler (transcranial Doppler Sonography) while walking on a treadmill.

Inclusion Criteria:

  • healthy subjects without brain disease

Exclusion Criteria:

  • brain disease and walking disfunctions
  Contacts and Locations
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Please refer to this study by its identifier: NCT01254968

Medical University of Silesia
Katowice, Silesia, Poland, 40-055
Sponsors and Collaborators
Medical University of Silesia
  More Information

Responsible Party: Medical University of Silesia, Department of Rehabilitation Identifier: NCT01254968     History of Changes
Other Study ID Numbers: BW-07-AM
Study First Received: November 29, 2010
Last Updated: December 6, 2010

Keywords provided by Medical University of Silesia:
blood flow in the middle cerebral artery of brain processed this record on September 21, 2017