Influence of Direction of Movement While Walking
The aim of the study is evaluation of cerebral blood flow (based on testing the rate of flow in middle cerebral arteries by transcranial Doppler ultrasound) during different forms of walking training - walk forwards and backwards, with closed and open eyes.
Changes in Blood Flow to the Brain
Changes Depending on the Form of Walking
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Influence of Direction of Movement While Walking Upon the Blood Flow Rate Through Brain, Examined by Transcranial Doppler Sonography in Young Healthy Subjects.|
- Transcranial Doppler sonography in young healthy subjects. [ Time Frame: 5 months ] [ Designated as safety issue: No ]Significant changes in blood flow to the brain depending on the form of walking and its conditions were observed. Changes in the right middle cerebral artery were more diverse than in the left artery. Difficulty in walking training forms gave long-term vasodilation.
|Study Start Date:||December 2008|
|Study Completion Date:||April 2009|
|Primary Completion Date:||January 2009 (Final data collection date for primary outcome measure)|
20 healthy subjects (11 men, 9 women, average age 23.94)
6 healthy subjects (3 men, 3 women, average age 23.6)
In the third minute of training walking a significant increase in blood flow velocity was recorded, both in right and left middle cerebral arteries. It was observed in the left artery during all forms of training. In the right artery it occurred only during three forms of difficult training, and was preceded by significant decrease in blood flow in the first minute of the gait with eyes closed. The output values of the rate of blood flow in both right and left middle cerebral arteries became progressively reduced in the successive stages of gait. Pressure and pulse rates did not correlate with the variables of blood flow velocity in middle cerebral arteries.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01254968
|Medical University of Silesia|
|Katowice, Silesia, Poland, 40-055|