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IOP Lowering Effects of Topical Anesthetics Used Frequently in the Ophthalmology Clinic

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01254149
First Posted: December 6, 2010
Last Update Posted: June 14, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
University of Nebraska
  Purpose
The primary purpose of this study is to determine whether topical ophthalmic anesthetics lower the intraocular pressure in the eye.

Condition
Normal Tension Glaucoma

Study Type: Observational
Study Design: Time Perspective: Cross-Sectional
Official Title: Intraocular Pressure Lowering Effects of Topical Anesthetics Used Frequently in the Ophthalmology Clinic

Resource links provided by NLM:


Further study details as provided by University of Nebraska:

Primary Outcome Measures:
  • Measured pressures in subjects' eyes with and without anesthetics. [ Time Frame: 30 minutes ]

Enrollment: 43
Study Start Date: January 2011
Study Completion Date: April 2012
Primary Completion Date: April 2012 (Final data collection date for primary outcome measure)
  Show Detailed Description

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   19 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Subjects 19 years of age and older with normal eyes and with ocular disease.
Criteria

Inclusion Criteria:

  • Subjects must be 19 years of age and older

Exclusion Criteria:

  • Corneal diseases including corneal transplants, corneal dystrophies, or trauma to the cornea that may prevent reliable tonometry of either eye.
  • Intolerant to topical Proparacaine and Benoxinate
  • Pregnant or nursing
  • 18 years of age and younger.
  • Physical limitation preventing ability to obtain reliable intraocular measurements (e.g. difficulty positioning subjects in front of the slit lamp or inability to keep eyes open during the intraocular pressure checks).
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01254149


Locations
United States, Nebraska
University of Nebraska Medical Center, Department of Ophthalmology
Omaha, Nebraska, United States, 68198
Sponsors and Collaborators
University of Nebraska
Investigators
Principal Investigator: Nathan Welch, MD UNMC Department of Ophthalmology and Visual Sciences
  More Information

Responsible Party: University of Nebraska
ClinicalTrials.gov Identifier: NCT01254149     History of Changes
Other Study ID Numbers: 577-10-FB
First Submitted: December 2, 2010
First Posted: December 6, 2010
Last Update Posted: June 14, 2012
Last Verified: June 2012

Additional relevant MeSH terms:
Low Tension Glaucoma
Optic Nerve Diseases
Eye Diseases
Anesthetics
Central Nervous System Depressants
Physiological Effects of Drugs