A Multicenter Observational Study of Invasive Candida Infections Among ICU Patients in China (china-scan)
|ClinicalTrials.gov Identifier: NCT01253954|
Recruitment Status : Unknown
Verified November 2009 by Southeast University, China.
Recruitment status was: Recruiting
First Posted : December 6, 2010
Last Update Posted : December 6, 2010
|Condition or disease|
Background of the study:
The incidence of invasive candida infection (ICI) in critically ill patients is increasing day by day. The crude mortality of ICI in ICU could be as high as 25%-75% depending on their age, underlying conditions, and so on. Candida albicans was by far the predominant species in most countries, causing up to two thirds of all cases of invasive candidiasis. However, a shift toward non-albicans Candida species has been observed. Although the studies of ICI cause universal attention recently, there is still no large-scale, multi-center epidemiological research in China focusing on IFI in critically ill patients, therefore we conducted a large-scale multi-center observational study of IFI in critically ill patients named "China Scan" (CHINA Survey of Candidiasis in ICU) to assess the current incidence, mortality, pathogen spectrum, management, and risk factors for ICI in China ICUs.
Objective of the study:
Determine the current incidence of IFI in ICUs in China. Describe the risk factors for IFI in China ICUs. Explore the pathogen spectrum of IFI in ICUs in China. Describe the in vitro antifungal susceptibility of Candida isolates. Describe the antifungal treatment for ICU patients with IFI. Evaluate in-hospital mortality among patients with IFI in ICUs.
|Study Type :||Observational|
|Estimated Enrollment :||300 participants|
|Official Title:||Epidemiology of Invasive Candida Infections in Critically Ill Patients: A Multicenter, Prospective, Observational Study in China|
|Study Start Date :||November 2009|
|Estimated Primary Completion Date :||April 2011|
|Estimated Study Completion Date :||April 2011|
ICU patients with IFI
- Determine the current incidence and in-hospital mortality of invasive candidas infection in ICUs in China. [ Time Frame: 300 charactors ]
- Describe the risk factors for ICI in China ICUs. Explore the pathogen spectrum of ICI in ICUs in China. Describe the in vitro antifungal susceptibility of Candida isolates. Describe the antifungal treatment for ICU patients with ICI. [ Time Frame: 300 charactors ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01253954
|Nanjing, Jiangsu, China, 210009|
|Contact: GUO F M, Dr 86-10-02583272201 firstname.lastname@example.org|