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A Research on the Hospital Pollution Control and Hygine Intervention of Chemotherapy Drugs Exposure

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ClinicalTrials.gov Identifier: NCT01253057
Recruitment Status : Unknown
Verified December 2010 by Taipei Medical University WanFang Hospital.
Recruitment status was:  Active, not recruiting
First Posted : December 3, 2010
Last Update Posted : December 3, 2010
Sponsor:
Information provided by:
Taipei Medical University WanFang Hospital

Brief Summary:

Several epidemiological studies found that exposure to antineoplastic agents were associated with some reproductive, carcinogenic effects, higher rates of advance micronuclei (MN), sister-chromatic-exchange (SCE) and spontaneous abortion. Cleaning staff were potentially exposed to these agents while cleaning ward, ward toilet or other area.

One medical center and one area hospitals in Taipei.Surface wipe samples were collected in the cleaning staff work area, such as ward environment and ward toilet. Urine and blood samples of subjects were collected for exposure examinations. Platinum-containing drugs (Cisplatin, Carboplatin, Oxaliplatin) were used as indicator drugs in environmental (surface wipe samples) and biological (urine and blood samples) samples.

A self-administered questionnaire was used to collect demographic data, working practices, medical and contact history, and perceived work-related symptoms of cleaning staff.

The results of this study will be to reduce exposure to cleaning staff.


Condition or disease
Sister-chromatic-exchange(SCE) Micronuclei(MN)

Study Type : Observational
Estimated Enrollment : 200 participants
Observational Model: Case Control
Official Title: A Research on the Hospital Pollution Control and Hygine Intervention of Chemotherapy Drugs Exposure
Study Start Date : October 2010
Estimated Study Completion Date : December 2011

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Group/Cohort
Experimental Group
Control Group




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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
cleaning staff
Criteria

Inclusion Criteria:

  • Only included those who signed the consent study

Exclusion Criteria:


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01253057


Locations
Taiwan
Taipei Medical University WanFang Hospital
Taipei, Taiwan
Sponsors and Collaborators
Taipei Medical University WanFang Hospital
Investigators
Principal Investigator: Ruey-Yu Chen Taipei Medical University

Responsible Party: Ruey-Yu Chen, Taipei Medical University School of Public Health
ClinicalTrials.gov Identifier: NCT01253057     History of Changes
Other Study ID Numbers: 99061
First Posted: December 3, 2010    Key Record Dates
Last Update Posted: December 3, 2010
Last Verified: December 2010

Keywords provided by Taipei Medical University WanFang Hospital:
cleaning staff
antineoplastic agents