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Non Invasive Ventilation After Cardiac Surgery (CPAP-CCH)

This study has been completed.
Information provided by (Responsible Party):
Giovanni Landoni, Università Vita-Salute San Raffaele Identifier:
First received: November 29, 2010
Last updated: October 13, 2015
Last verified: October 2015
Patients with respiratory failure following cardiac surgery are randomized to receive standard therapy versus non invasive ventilation. The hypothesis is that patients receiving non invasive ventilation will perform better than those who received standard therapy.

Condition Intervention
Respiratory Failure. Procedure: non invasive ventilation

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Effectiveness of Continuous Positive Airway Pressure Outside the Intensive Care Unit After Cardiac Surgery

Resource links provided by NLM:

Further study details as provided by Giovanni Landoni, Università Vita-Salute San Raffaele:

Study Start Date: September 2010
Study Completion Date: December 2013
Primary Completion Date: December 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
No Intervention: Best available treatment
Experimental: non invasive ventilation Procedure: non invasive ventilation
continuous positive airways pressure
Other Names:
  • NIV
  • CPAP


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • hypoxia

Exclusion Criteria:

  • pneumothorax
  • cardiocirculatory instability
  • no written consent
  Contacts and Locations
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Please refer to this study by its identifier: NCT01249794

Ospedale San Raffaele di Milano, Italy
Milano, Italy, 20132
Sponsors and Collaborators
Università Vita-Salute San Raffaele
Principal Investigator: Ottavio Alfieri, MD Vita-Salute San Raffaele, Milano, Italia
  More Information

Responsible Party: Giovanni Landoni, MD, Università Vita-Salute San Raffaele Identifier: NCT01249794     History of Changes
Other Study ID Numbers: GO/URC/ER/mm 183/DG
Study First Received: November 29, 2010
Last Updated: October 13, 2015

Keywords provided by Giovanni Landoni, Università Vita-Salute San Raffaele:
non invasive ventilation
cardiac surgery
continuous positive airway pressure

Additional relevant MeSH terms:
Respiratory Insufficiency
Respiration Disorders
Respiratory Tract Diseases processed this record on August 23, 2017