"Volatile Anesthetic Protection Of Renal Transplants: VAPOR-1-trail
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ClinicalTrials.gov Identifier: NCT01248871 |
Recruitment Status
:
Completed
First Posted
: November 25, 2010
Last Update Posted
: December 19, 2012
|
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Kidney Donation/Transplantation | Drug: procedure:sevoflurane-remifentanil/sufentanil Drug: volatile agent only during reperfusion Drug: propofol-remifentanil/sufentanil | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 120 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Single (Participant) |
Primary Purpose: | Prevention |
Official Title: | "Volatile Anesthetic Protection Of Renal Transplants: VAPOR-1-trail |
Study Start Date : | September 2010 |
Actual Primary Completion Date : | October 2012 |
Actual Study Completion Date : | October 2012 |

Arm | Intervention/treatment |
---|---|
Active Comparator: SEVO
sevoflurane-remifentanil/sufentanil combination
|
Drug: procedure:sevoflurane-remifentanil/sufentanil
Active Comparator
|
Active Comparator: SERE
volatile agent only during reperfusion
|
Drug: volatile agent only during reperfusion
Active Comparator
|
Active Comparator: propofol
propofol-remifentanil/sufentanil
|
Drug: propofol-remifentanil/sufentanil
Active Comparator
|
- To compare the renal protective properties of two currently used anaesthetic techniques [ Time Frame: participants will be followed for the duration of hospital stay ]

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Ages Eligible for Study: | 18 Years to 80 Years (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- All patients: Age > 18 years
Exclusion Criteria:
- patient refusal
- BMI< 17, >35
- neurological disorder
- recent use of psycho-active medication, including alcohol.
- Donor-recipient couples from the ABO-incompatible program
- Altruistic donor

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01248871
Netherlands | |
University Medical Center Groningen | |
Groningen, Netherlands, 9713 EZ |
Principal Investigator: | M.M.R.F Struys, Prof.dr. | University Medical Center Groningen | |
Principal Investigator: | R,J. Ploeg, Prof.dr | University Medical Center Groningen |
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | MMRF Struys, Prof.dr., University Medical Centre Groningen |
ClinicalTrials.gov Identifier: | NCT01248871 History of Changes |
Other Study ID Numbers: |
VAPOR 001 |
First Posted: | November 25, 2010 Key Record Dates |
Last Update Posted: | December 19, 2012 |
Last Verified: | December 2012 |
Keywords provided by MMRF Struys, University Medical Centre Groningen:
renal transplantation Volatile anesthetic |
Additional relevant MeSH terms:
Propofol Remifentanil Sufentanil Anesthetics Sevoflurane Hypnotics and Sedatives Central Nervous System Depressants Physiological Effects of Drugs Anesthetics, Intravenous |
Anesthetics, General Analgesics, Opioid Narcotics Analgesics Sensory System Agents Peripheral Nervous System Agents Platelet Aggregation Inhibitors Anesthetics, Inhalation Adjuvants, Anesthesia |