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Inflammatory Markers in Exhaled Breath Condensates From Asthmatic Patients

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01246414
First Posted: November 23, 2010
Last Update Posted: November 23, 2010
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
Mahidol University
Information provided by:
Chulalongkorn University
  Purpose
This study aims to compare the inflammatory mediators in exhaled breathe condensates from allergic and non-allergic asthmatic patients.

Condition
Asthma

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Inflammatory Markers in Exhaled Breath Condensates From Asthmatic Patients

Further study details as provided by Chulalongkorn University:

Primary Outcome Measures:
  • Levels of inflammatory cytokines in exhaled breathe condensates [ Time Frame: 4 months ]

Biospecimen Retention:   Samples Without DNA
Exhaled breathe condensates

Enrollment: 38
Study Start Date: January 2010
Study Completion Date: May 2010
Primary Completion Date: April 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts
Allergic asthma
Patients with allergic asthma
Non-allergic asthma
Patients with non-allergic asthma
Non-asthmatic controls
Non-asthmatic controls

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   15 Years to 65 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Asthmatic patients in Allergy clinic, King Chulalongkorn Memorial Hospital (10 allergic and 10 non-allergic) and 10 non-asthmatic controls will be enrolled to this study to collect exhaled breathe condensates (EBC) and measure levels of inflammatory cytokines in EBC
Criteria

Inclusion Criteria:

  1. Have been diagnosed as asthma at least 6 months before enrolled to the study
  2. Known skin prick test results to aeroallergens ; either positive or negative
  3. 15-65 years of age

Exclusion Criteria:

  1. On oral or inhaled corticosteroids within 1 month before the study
  2. Having asthma exacerbation
  3. Being pregnant
  4. Suffering from severe systemic disease/ in bad health
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01246414


Locations
Thailand
Chulalongkorn University
Bangkok, Thailand, 10330
Sponsors and Collaborators
Chulalongkorn University
Mahidol University
Investigators
Principal Investigator: Jettanong Klaewsongkram, MD Chulalongkorn University
  More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Jettanong Klaewsongkram, MD., Chulalongkorn University
ClinicalTrials.gov Identifier: NCT01246414     History of Changes
Other Study ID Numbers: Chula-ARC 001/10
First Submitted: January 4, 2010
First Posted: November 23, 2010
Last Update Posted: November 23, 2010
Last Verified: November 2010

Keywords provided by Chulalongkorn University:
Asthma
Exhaled breath condensates
Cytokines