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The Effects of Vibration on Hypoxia

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01245491
Recruitment Status : Completed
First Posted : November 22, 2010
Last Update Posted : January 14, 2011
Information provided by:

Study Description
Brief Summary:

The purpose of this study is:

  1. To study the effect of whole-body vibration on partial pressure of oxygen in arterial blood (PaO2), under hypobaric hypoxic conditions.
  2. To study the effects of whole-body vibration and hypobaric hypoxia on visual contrast sensitivity.
  3. To se if there is an increase in cytokines and other biomarkers under different hypobaric hypoxic conditions Our main hypothesis is that whole-body vibration may cause PaO2 to drop to a lower level, at a given altitude; than would be the case if there were no vibration present.

Condition or disease Intervention/treatment
Hypoxia Other: Vibration

Study Design

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 13 participants
Intervention Model: Crossover Assignment
Masking: Single (Participant)
Primary Purpose: Basic Science
Official Title: The Effects of Vibration on Hypoxia
Study Start Date : October 2010
Primary Completion Date : December 2010
Study Completion Date : December 2010
Arms and Interventions

Intervention Details:
    Other: Vibration
    Whole-body vibration, 17 Hz, 1.1ms-2

Outcome Measures

Primary Outcome Measures :
  1. PaO2 [ Time Frame: 14 minutes ]
    Assessed at six different altitudes

  2. PaO2 [ Time Frame: 35 minutes ]
    Assessed at six dfferent altitudes

Secondary Outcome Measures :
  1. Ventilation [ Time Frame: 14 minutes ]
    Assessed at six different altitudes, over a period of three minutes.

  2. Ventilation [ Time Frame: 35 minutes ]
    Assessed over a periode of three minutes, at six different altitudes.

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

Exclusion Criteria:

  • Stay at altitude over 2000 m last two weeks prior to study-start.
  • Severe head injury
  • Cardiovascular disease
  • lung disease
  • Decompression sickness
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01245491

Sponsors and Collaborators
Institute of Aviation Medicine, Oslo, Norway
Principal Investigator: Tor A Hansen, Msc. Institute of Aviation Medicine
More Information

Responsible Party: Anthony S. Wagstaff, Institute of Aviation Medicine
ClinicalTrials.gov Identifier: NCT01245491     History of Changes
Other Study ID Numbers: REK-2010/2021b
First Posted: November 22, 2010    Key Record Dates
Last Update Posted: January 14, 2011
Last Verified: January 2011

Additional relevant MeSH terms:
Signs and Symptoms, Respiratory
Signs and Symptoms