Glycemic Response of Bean-and-rice Meals in Type 2 Diabetes Mellitus
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|ClinicalTrials.gov Identifier: NCT01241253|
Recruitment Status : Completed
First Posted : November 16, 2010
Last Update Posted : January 10, 2018
The study uses a randomized, placebo-controlled experimental design consisting of 4 different test treatments matched on carbohydrate (CHO) content. The three beans are similar in their CHO content amount for ½ cup at ~20 grams CHO. Each of the bean varieties will be served in a ~½ cup serving size with ~ ½ cup of plain steamed white rice (30 grams CHO) for a total of 50 grams of CHO per meal for each of the three test treatments. The 4th placebo or control treatment consists of ~ 7/8 cup of rice alone, an amount consistent with the CHO content of the test meals. Most diabetic meal plans recommend no more than 45-60 grams of CHO per meal. Fifty grams of CHO is a standard amount for glycemic response testing in general.
The investigators hypotheses were:
- The test meals containing the three bean types in combination with white rice will decrease the participants' glycemic response when eaten as part of a meal.
- The reduction in post-prandial glycemia will not differ between bean types in the elicited responses among individuals with type 2 diabetes.
|Condition or disease||Intervention/treatment||Phase|
|Blood Glucose Type 2 Diabetes Mellitus||Other: Whole cooked beans with rice meals||Phase 2|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||17 participants|
|Intervention Model:||Crossover Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||Glycemic Response of Bean-and-rice Meals in Persons With Type 2 Diabetes Mellitus|
|Study Start Date :||November 2009|
|Actual Primary Completion Date :||April 2010|
|Actual Study Completion Date :||April 2010|
No Intervention: Cross-over study
beans and rice in a 50 gram carbohydrate dose
Other: Whole cooked beans with rice meals
Three types of bean-and-rice meals all equal to 50 grams available CHO. Control treatment was 50 grams available CHO in the form of white rice alone.
Other Name: Bush Brothers & Company brand canned beans
- Net blood glucose changes over time [ Time Frame: fasting baseline glucose at time 0, then 30, 60, 90, 120, 150, and 180 minutes postprandial ]Capillary blood samples were collected via fingerstick using Safe-T-Fill® Lithium Heparin Mini Capillary Collection 125µl tubes (RAM Scientific, Yonkers, NY). Whole blood samples were analyzed for glucose content using the Yellow Springs Instrument Stat Plus Analyzer (YSI Life Sciences, Yellow Springs, OH) immediately after blood collection.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01241253
|United States, Arizona|
|Arizona State University, Nutrition Program|
|Mesa, Arizona, United States, 85212|
|Principal Investigator:||Donna M Winham, DrPH||Arizona State University|