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The Variation of Movement Related Cortical Potential, Cortico-cortical Inhibition, and Motor Evoked Potential in Intracerebral Implantation of Antologous Peripheral Blood Stem Cells(CD34)in Old Ischemic Stroke

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified November 2010 by China Medical University Hospital.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT01239602
First Posted: November 11, 2010
Last Update Posted: November 11, 2010
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
China Medical University Hospital
  Purpose
Stem cell theray in old stroke patients is a study to treat stroke patients approved before in our hospital. We recruit these patients who received stem cell therapy and completed the study. We adopted movement-related cortical potential,and cortico-cortical inhibition to assess the stroke patients with or without stem cell therapy. Further analyzing the correlation of the motor related cortical potential and cortico-cortical inhibition among them. We wanted to find out if there are changes in cortical excitability in subjects with chronic stroke after stem cell therapy.

Condition
Stroke

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective

Further study details as provided by China Medical University Hospital:

Estimated Enrollment: 36
Study Start Date: October 2010
Estimated Study Completion Date: October 2010
Estimated Primary Completion Date: October 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts
Normal control
with Stem cell therapy plus G-CSF
G-CSF along

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   30 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
36 patients suffered from old cerebral infarction (middle cerebral artery territory as documented on the T2 weight image [T2WI] of MRI) between 6 months and 5 years of onset who had initial scores on the National Institute of Health stroke scale (NIHSS) of between 9 and 20.
Criteria

Inclusion Criteria:

  • 1.old cerebral infarction (middle cerebral artery territory as documented on the T2 weight image [T2WI] of MRI) 2.between 6 months and 5 years of onset 3.National Institute of Health stroke scale (NIHSS) of between 9 and 20.

Exclusion Criteria:

  • 1.Seizure history 2. Pacemaker insertion
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01239602


Locations
Taiwan
China Medical University Hospital Recruiting
Taichung, Taiwan, 404
Contact: Jui-cheng Chen, M.D.    886422052121 ext 5039      
Sponsors and Collaborators
China Medical University Hospital
  More Information

Responsible Party: China Medical University Hospital
ClinicalTrials.gov Identifier: NCT01239602     History of Changes
Other Study ID Numbers: DMR99-IRB-200
First Submitted: November 10, 2010
First Posted: November 11, 2010
Last Update Posted: November 11, 2010
Last Verified: November 2010

Keywords provided by China Medical University Hospital:
changes in cortical excitability in subjects with chronic stroke after stem cell therapy

Additional relevant MeSH terms:
Stroke
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases