Pathophysiologic Changes in the Respiratory System During Therapeutic Interventions
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Pathophysiologic Changes in the Respiratory System During Therapeutic Interventions|
- Intrabronchial airway pressure [ Time Frame: 2013 ] [ Designated as safety issue: No ]
|Study Start Date:||May 2011|
|Study Completion Date:||May 2016|
|Primary Completion Date:||May 2016 (Final data collection date for primary outcome measure)|
mechanically ventilated patients
ICU patients on mechanical ventilation. Daily endotracheal suctioning performed to reduce secretions. Data recorded during these therapeutic interventions.
Airway pressures change during fiberoptic bronchoscopy and endotracheal suctioning. In this study such pressure changes are examined in a mechanical lung model and in a population of ICU patients on mechanical ventilation. A systematic recording of airway pressures, tidal volumes and blood gases are carried out during ordinary therapeutic procedures requested by the staff physician. No additional study interventions are carried out.
The aim of the project is to examine negative effects of pressure/volume changes.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01239433
|Oslo University Hospital - Ulleval|
|Oslo, Norway, 0407|
|Principal Investigator:||Espen R Nakstad, MD||Oslo University Hospital - Ulleval, Norway|
|Study Director:||Helge Opdahl, MD, PhD||Ullevaal University Hospital|