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Autologous Serum Skin Testing in Patients With Atopic Dermatitis Autologous Serum Skin Testing in Patients With Atopic Dermatitis

This study has been completed.
Information provided by:
Yuzuncu Yıl University Identifier:
First received: November 9, 2010
Last updated: NA
Last verified: May 2009
History: No changes posted
Recently, IgE-type autoantibodies against self proteins have been detected in the serum of the atopic dermatitis patients. The role of this IgE autoantibodies involved in the pathogenesis of atopic dermatitis is not known, yet. But, there may be a correlation between the severity of the disease and the serum levels of this autoantibodies. The autologous serum skin testing is applied to both atopic dermatitis patients and healthy control and the results are estimated in this study.The investigators detected 70% positive autologous serum skin testing in atopic dermatitis patients and test positivity was higher in patients with atopy history, moderately severe disease calculated by SCORAD index and high serum IgE levels.

Atopic Dermatitis, Serum Skin Test

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Yuzuncu Yıl University:

Enrollment: 90
Study Start Date: April 2009
Study Completion Date: August 2010
Primary Completion Date: June 2010 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   1 Year to 45 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population

Inclusion Criteria:

  • Sixty AD patients and 30 healthy individuals

Exclusion Criteria:

  • . The patients showing evidence of any other disease are not included to our study. No drug was allowed fourteen days prior to the test, including antihistamines and steroids.
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No Contacts or Locations Provided
  More Information

Responsible Party: Silvan State Hospital, Dermatology department Identifier: NCT01238263     History of Changes
Other Study ID Numbers: yavuzyesilova
Study First Received: November 9, 2010
Last Updated: November 9, 2010

Keywords provided by Yuzuncu Yıl University:
Atopic dermatitis, autologous serum skin testing, IgE autoantibodies

Additional relevant MeSH terms:
Dermatitis, Atopic
Skin Diseases
Skin Diseases, Genetic
Genetic Diseases, Inborn
Skin Diseases, Eczematous
Hypersensitivity, Immediate
Immune System Diseases processed this record on June 22, 2017