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East-West Hepatocellular Carcinoma Study Group

This study has been completed.
Information provided by:
University of Milan Identifier:
First received: November 8, 2010
Last updated: NA
Last verified: December 2009
History: No changes posted
The current treatment guidelines of hepatocellular carcinoma (HCC) of the American and European Associations for the Study of Liver Disease are based on the Barcelona-Clinic-Liver-Cancer classification (BCLC), which does not recommend surgery in patients with large, multinodular and macrovascular invasive disease. The aim of this study was to investigate the role of hepatic resection in a large retrospective multicentric cohort of patients resected for HCC regardless of the BCLC indications.

Carcinoma, Hepatocellular

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective

Further study details as provided by University of Milan:

Primary Outcome Measures:
  • Overall survival of resected patients for HCC
    The primary endpoint of the study was the overall survival of patients resected for HCC in any stage of the BCLC classification.

Secondary Outcome Measures:
  • Disease-free survival of resected patients for HCC
    The secondary endpoint was the disease-free survival of patients resected for HCC among the BCLC stages.


Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients affected by HCC

Inclusion Criteria:

  • clinical diagnosis of hepatocellular carcinoma
  • candidate to liver resection as a curative treatment

Exclusion Criteria:

  • uncertain diagnosis of hepatocellular carcinoma
  • uncertain follow-up data
  Contacts and Locations
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No Contacts or Locations Provided
  More Information

Responsible Party: GUIDO TORZILLI MD, PHD, UNIVERSITY OF MILAN Identifier: NCT01237132     History of Changes
Other Study ID Numbers: HCC EWE
Study First Received: November 8, 2010
Last Updated: November 8, 2010

Additional relevant MeSH terms:
Carcinoma, Hepatocellular
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Liver Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Digestive System Diseases
Liver Diseases processed this record on August 16, 2017