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Free Flap Microcirculatory Monitoring Correlates to Free Flap Temperature Assessment

This study has been completed.
Information provided by (Responsible Party):
Hannover Medical School Identifier:
First received: November 4, 2010
Last updated: February 23, 2017
Last verified: November 2010
In case of free flap failure, time is of utmost importance as salvage rates have been reported to be inversely related to the time interval between the onset of ischemia and its clinical recognition. Consecutively, monitoring of free flaps remains of major importance. Currently, combined Laser-Doppler and Spectrophotometry is available to determine microcirculation of free flaps in reconstructive surgery as a scientific method of reliable assessment of flap perfusion. The investigators thought to analyze the correlation of free flap skin temperature and free frap microcirculation as an accurate tool of postoperative flap monitoring.

Flap Monitoring

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Free Flap Microcirculatory Monitoring Correlates to Free Flap Temperature Assessment

Further study details as provided by Hannover Medical School:

Primary Outcome Measures:
  • Correlation of cutaneous microcirculation to free flap temperature [ Time Frame: 4 months ]

Enrollment: 54
Study Start Date: September 2010
Study Completion Date: November 2010
Primary Completion Date: November 2010 (Final data collection date for primary outcome measure)
Healthy subjects
Subjects suffering from Diabetes mellitus
Subjects suffering from peripheral arterial occlusive disease


Ages Eligible for Study:   16 Years to 65 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Patients suffering from a soft tissue defect at any location of the body receiving free flap soft-tissue defect coverage at the Department of Plastic, Hand and Reconstructive Surgery, Medical School Hannover, Germany.

Inclusion Criteria:

  • Age between 16 and 65 years

Exclusion Criteria:

  • soft tissue inflammation or osteomyelitis, peripheral arterial occlusive disease, vasculitis, chronic kidney or liver disease, cardiac dysfunction, arterial hypotension and any type of vasoactive medication, i.e. ß-blockers, calcium channel blockers, nitroglycerin or equal.
  Contacts and Locations
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Please refer to this study by its identifier: NCT01235299

Medical School Hannover
Hannover, Germany, 30625
Sponsors and Collaborators
Hannover Medical School
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Hannover Medical School Identifier: NCT01235299     History of Changes
Other Study ID Numbers: Kraemer002
Study First Received: November 4, 2010
Last Updated: February 23, 2017 processed this record on September 19, 2017