Oocyte Cryopreservation (egg freezing)
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|ClinicalTrials.gov Identifier: NCT01232972|
Recruitment Status : Terminated (Study technique has been declared part of standard care)
First Posted : November 2, 2010
Last Update Posted : April 23, 2013
|Condition or disease||Intervention/treatment||Phase|
|Fertility||Procedure: vitrification of oocytes||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||23 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Supportive Care|
|Official Title:||Oocyte Cryopreservation|
|Study Start Date :||October 2010|
|Actual Primary Completion Date :||March 2013|
|Actual Study Completion Date :||March 2013|
Experimental: oocyte freezing
includes any women who elects to preserve her fertility by vitrifying her unfertilized eggs.
Procedure: vitrification of oocytes
eggs will be preserved via vitrification the day they are retrieved from the participant
- Successful pregnancy [ Time Frame: until the patient reaches 50 years of age ]Eggs will be frozen via vitrification for those females electing to preserve their fertility; patients will return following an unspecified time period, when they are ready to use their frozen eggs. At that time, the eggs will be thawed and fertilized (with the sperm source of the participant's choice) to create embryos. This time frame will be unique to each individual; however, the Center has a policy whereby no embryo transfer will be performed beyond the age of fifty (50).
- oocyte survival [ Time Frame: up to 50 years of age ]the number of eggs that successfully survive the frozen-thawing procedure (vitrification).
- fertilization [ Time Frame: up to 50 years of age ]to calculate the rate for the number of oocytes that are successfully fertilized (via ICSI) following survival of the frozen-thaw procedure.
- blastocyst formation [ Time Frame: up to 50 years of age ]calculates the number of successfully fertilized embryos that grow into blastocysts (day 5 of culture), created from eggs that underwent and survived vitrification.
- implantation [ Time Frame: up to 50 years of age ]to determine the implantation rate of embryos that were created from vitrified oocytes.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01232972
|United States, New York|
|Center for Human Reproduction|
|Manhasset, New York, United States, 11030|
|Principal Investigator:||Avner Hershlag, MD||Center for Human Reproduction|