Polarization Sensitive Retinal Tomography for Glaucoma Diagnosis (PSOCT)
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|ClinicalTrials.gov Identifier: NCT01222065|
Recruitment Status : Completed
First Posted : October 18, 2010
Last Update Posted : March 27, 2012
The proposed human clinical studies have three main objectives:
- To determine reproducibility of peripapillary birefringence maps and identify features that measure the health of the RNFL.
- To determine the normal variation in the birefringence maps with age.
- To develop and test a classifier for glaucoma based on the birefringence maps using a case-control clinical trial.
This study is a case-control study intended to optimize feature selection for a future multi-center blinded study. The proposed clinical study does not measure conversion from normal to glaucoma.
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||85 participants|
|Observational Model:||Case Control|
|Official Title:||Polarization Sensitive Retinal Tomography for Glaucoma Diagnosis|
|Study Start Date :||August 2007|
|Actual Primary Completion Date :||December 2010|
|Actual Study Completion Date :||March 2011|
Two groups will be studies: patients with glaucomatous visual field loss and age and gender matched normal patients without visual field loss
- Sensitivity/specificity of PSOCT to classify glaucoma vs. non-glaucoma [ Time Frame: The time frame to assess the effectiveness of the diagnostic algorithm is 1 year ]Features from RNFL phase retardation and birefringence maps will be combined into a diagnostic algorithm to differentiate glaucoma vs. non-glaucoma
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01222065
|United States, Texas|
|Eye Institute of Austin|
|Austin, Texas, United States, 78757|
|Principal Investigator:||Henry G Rylander, MD||University of Texas at Austin|