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What Influences Patient Outcome in Obstructive Airway Disease?

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ClinicalTrials.gov Identifier: NCT01221480
Recruitment Status : Completed
First Posted : October 15, 2010
Last Update Posted : December 1, 2016
Sponsor:
Information provided by (Responsible Party):
Brian J Lipworth, University of Dundee

Brief Summary:
The aim of this observational study is to utilise the established record linkage data available in Tayside to investigate hospital admissions, exacerbations and mortality in COPD.

Condition or disease
COPD

Study Type : Observational
Actual Enrollment : 5977 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Beta-Blockers Reduce Mortality and Exacerbations When Added to Stepwise Inhaled Therapy for COPD Without Adverse Effects on Lung Function.
Study Start Date : August 2010
Actual Primary Completion Date : October 2010
Actual Study Completion Date : October 2010

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Group/Cohort
Beta Blocker Use
No beta blocker use



Primary Outcome Measures :
  1. All-cause Mortality

Secondary Outcome Measures :
  1. Hospital Admissions
  2. COPD exacerbations


Information from the National Library of Medicine

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Ages Eligible for Study:   50 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
COPD patients within NHS Tayside, UK
Criteria

Inclusion Criteria:

  • Data collected through TARDIS database

Exclusion Criteria:

  • History of asthma or malignancy. Less than 50 years of age

Responsible Party: Brian J Lipworth, Professor (Clinical) Airway allergy and COPD, University of Dundee
ClinicalTrials.gov Identifier: NCT01221480     History of Changes
Other Study ID Numbers: SHO002
First Posted: October 15, 2010    Key Record Dates
Last Update Posted: December 1, 2016
Last Verified: November 2016

Additional relevant MeSH terms:
Adrenergic beta-Antagonists
Adrenergic Antagonists
Adrenergic Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs