Evaluation of Donated Human Embryos Following in Vitro Fertilization
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01219361|
Recruitment Status : Enrolling by invitation
First Posted : October 13, 2010
Last Update Posted : March 26, 2018
|Condition or disease|
|Validation of Laboratory Techniques Validation of Laboratory Methods Assessment of Laboratory Staff Proficiency|
Undergoing IVF treatment often results in the production of more embryos than can safely be transferred at one time. These extra embryos are often cryopreserved for future use. In the event that a couple decides that they do not want to proceed with using cryopreserved embryos, these embryos can be discarded, donated to another couple, or donated to research.
Embryos that are donated to research are used to identify a group of parameters that have significant predictive value for assisted reproductive technology outcomes. We hope to develop future laboratory techniques as we gain a better knowledge of gamete development, fertilization and implantation. We will test, standardize and implement better methods for freezing embryos prior to employing these techniques in a clinical setting. We hope to develop new methods to optimize the determination of genes and chromosomes in embryos. We will test the proficiency of laboratory staff on techniques and/or procedures done in the IVF laboratory. This study WILL NOT:create embryos for research, transfer embryos to an individual, develop cell lines or clones.
|Study Type :||Observational|
|Estimated Enrollment :||5000 participants|
|Official Title:||Evaluation of Donated Human Embryos for Study of Normal and Abnormal Differentiation and Development Following in Vitro Fertilization.|
|Study Start Date :||July 2005|
|Estimated Primary Completion Date :||December 2020|
|Estimated Study Completion Date :||December 2025|
- Freezing methods for embryos [ Time Frame: duration of the study ]To test, standardize and implement better methods for the freezing of embryos prior to these techniques being implemented in the clinical setting.
- Development of New Methods [ Time Frame: duration of the study ]The development of new methods to optimize the determination of genes and chromosomes in embryos
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01219361
|United States, New Jersey|
|Reproductive Medicine Assoicates of New Jersey|
|Basking Ridge, New Jersey, United States, 07920|
|United States, Pennsylvania|
|Reproductive Medicine Assoicates of PA at Lehigh Valley|
|Allentown, Pennsylvania, United States, 18104|
|Principal Investigator:||Richard T Scott, MD||Reproductive Medicine Associates of New Jersey|