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Non-Specific Chronic Back Pain; Insight From Spatial Aspects of Lumbar Spinal Muscle Activation

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01214213
First Posted: October 4, 2010
Last Update Posted: September 27, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Inge Ringheim, The Hospital of Vestfold
  Purpose
There is evidence for altered muscle activity patterns in individuals with non-specific chronic back pain (NSCBP). It is unknown why these alterations in activation pattern occur and how they may be linked to pain experience and to the development of CNSBP. The main objective of this study is to investigate the spatial aspects of muscle activation in relation to fatigue/endurance and CNSBP. A novel approach, utilizing a new multi-channel surface-EMG (MCsEMG) technique will be applied in this project to get insight in fundamental mechanisms related to motor control and fatigue/endurance. In this project data from healthy persons and from patients with NSCBP will be collected and analyzed. NSCBP patients will be compared to healthy persons. To minimize heterogeneity between groups the subject's age range will be from 30 - 50 years. The investigators main hypothesis is that motor control mechanisms of the lumbar muscles are disturbed in NSCBP patients compared to normals, explaining the reduced tolerance for static postures. There has been little investigation of the lumbar musculature with MCsEMG recordings. The lumbar musculature has a complex organization; many, relatively small muscles, in a restricted area. Utilizing two HDsEMG grids with 252 Ag/AgCl contacts will be the superior non-invasive method to investigate motor control mechanisms in this region, and further the investigators understanding of neuromuscular adaptations related to NSCBP. The project may demonstrate changes that will lead us to new insight and new strategies for the treatment of back pain.

Condition Phase
Low Back Pain Phase 1

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: NON-SPECIFIC CHRONIC BACK PAIN; INSIGHT FROM SPATIAL ASPECTS OF LUMBAR SPINAL MUSCLE ACTIVATION

Resource links provided by NLM:


Further study details as provided by Inge Ringheim, The Hospital of Vestfold:

Enrollment: 57
Study Start Date: September 2009
Study Completion Date: August 2014
Primary Completion Date: January 2014 (Final data collection date for primary outcome measure)
  Eligibility

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Ages Eligible for Study:   30 Years to 50 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Chronic non-spesific low back pain and healthy control subjects
Criteria

Inclusion Criteria:

  • patients
  • diagnosed with chronic NSCBP >3 months duration
  • healthy controls
  • no back pain.

Exclusively exclusion criteria for this group will be back pain in the previous year or back pain lasting longer than one week in previous 3 years.

Exclusion Criteria:

  • anamnesis of medical or drug abuse
  • surgery on the musculoskeletal system of the trunk
  • known congenital malformation of the spine or scoliosis
  • body mass index >27 kg/m2
  • systemic-neurological-degenerative disease
  • history of stroke
  • psychiatric disorder
  • pregnancy and abnormal blood pressure.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01214213


Locations
Norway
Vestfold Hospital Trust, Kysthospitalet
Stavern, Norway, 3291
Sponsors and Collaborators
Oslo University Hospital
Investigators
Study Chair: Aage Indahl, Phd
  More Information

Responsible Party: Inge Ringheim, MSc, The Hospital of Vestfold
ClinicalTrials.gov Identifier: NCT01214213     History of Changes
Other Study ID Numbers: MULTI2009
First Submitted: October 1, 2010
First Posted: October 4, 2010
Last Update Posted: September 27, 2016
Last Verified: September 2016

Additional relevant MeSH terms:
Back Pain
Low Back Pain
Pain
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms