Non-Specific Chronic Back Pain; Insight From Spatial Aspects of Lumbar Spinal Muscle Activation

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01214213
Recruitment Status : Completed
First Posted : October 4, 2010
Last Update Posted : September 27, 2016
Information provided by (Responsible Party):
Inge Ringheim, The Hospital of Vestfold

Brief Summary:
There is evidence for altered muscle activity patterns in individuals with non-specific chronic back pain (NSCBP). It is unknown why these alterations in activation pattern occur and how they may be linked to pain experience and to the development of CNSBP. The main objective of this study is to investigate the spatial aspects of muscle activation in relation to fatigue/endurance and CNSBP. A novel approach, utilizing a new multi-channel surface-EMG (MCsEMG) technique will be applied in this project to get insight in fundamental mechanisms related to motor control and fatigue/endurance. In this project data from healthy persons and from patients with NSCBP will be collected and analyzed. NSCBP patients will be compared to healthy persons. To minimize heterogeneity between groups the subject's age range will be from 30 - 50 years. The investigators main hypothesis is that motor control mechanisms of the lumbar muscles are disturbed in NSCBP patients compared to normals, explaining the reduced tolerance for static postures. There has been little investigation of the lumbar musculature with MCsEMG recordings. The lumbar musculature has a complex organization; many, relatively small muscles, in a restricted area. Utilizing two HDsEMG grids with 252 Ag/AgCl contacts will be the superior non-invasive method to investigate motor control mechanisms in this region, and further the investigators understanding of neuromuscular adaptations related to NSCBP. The project may demonstrate changes that will lead us to new insight and new strategies for the treatment of back pain.

Condition or disease
Low Back Pain

Study Type : Observational
Actual Enrollment : 57 participants
Observational Model: Case Control
Time Perspective: Cross-Sectional
Study Start Date : September 2009
Actual Primary Completion Date : January 2014
Actual Study Completion Date : August 2014

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Back Pain
U.S. FDA Resources

Information from the National Library of Medicine

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Ages Eligible for Study:   30 Years to 50 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Chronic non-spesific low back pain and healthy control subjects

Inclusion Criteria:

  • patients
  • diagnosed with chronic NSCBP >3 months duration
  • healthy controls
  • no back pain.

Exclusively exclusion criteria for this group will be back pain in the previous year or back pain lasting longer than one week in previous 3 years.

Exclusion Criteria:

  • anamnesis of medical or drug abuse
  • surgery on the musculoskeletal system of the trunk
  • known congenital malformation of the spine or scoliosis
  • body mass index >27 kg/m2
  • systemic-neurological-degenerative disease
  • history of stroke
  • psychiatric disorder
  • pregnancy and abnormal blood pressure.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01214213

Vestfold Hospital Trust, Kysthospitalet
Stavern, Norway, 3291
Sponsors and Collaborators
Oslo University Hospital
Study Chair: Aage Indahl, Phd

Responsible Party: Inge Ringheim, MSc, The Hospital of Vestfold Identifier: NCT01214213     History of Changes
Other Study ID Numbers: MULTI2009
First Posted: October 4, 2010    Key Record Dates
Last Update Posted: September 27, 2016
Last Verified: September 2016

Additional relevant MeSH terms:
Back Pain
Low Back Pain
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms