Effect of Adaptive Servoventilation on Cardiac Function in Chronic Heart Failure and Cheyne-Stokes Respiration

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified September 2010 by Military Institute of Medicine, Poland.
Recruitment status was:  Recruiting
Information provided by:
Military Institute of Medicine, Poland
ClinicalTrials.gov Identifier:
First received: September 30, 2010
Last updated: NA
Last verified: September 2010
History: No changes posted
Sleep disordered breathing is common in patients with chronic heart failure. Adaptive servoventilation is a novel method of treatment central sleep apnoea, especially associated with Cheyne-Stokes-respiration. The aim of the study is to investigate effect of adaptive servoventilation on cardiac function, exercise tolerance and quality of life in patients with chronic heart failure.

Condition Intervention
Chronic Heart Failure
Central Sleep Apnea
Cheyne-Stokes Respiration
Device: Adaptive servoventilation

Study Type: Interventional
Official Title: Effect of Adaptive Servoventilation on Cardiac Function, Exercise Tolerance and Quality of Life in Patients With Chronic Heart Failure and Cheyne-Stokes Respiration

Resource links provided by NLM:

Further study details as provided by Military Institute of Medicine, Poland:

Arms Assigned Interventions
Experimental: ASV Device: Adaptive servoventilation
Background expiratory positive airway pressure with some inspiratory pressure support when needed


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All

Inclusion Criteria:

  • chronic heart failure with ejection fraction ≤45%
  • optimal medical treatment for at least 1 month
  • clinical diagnosis of Cheyne-Stokes respiration

Exclusion Criteria:

  • unstable heart failure
  • stroke
  • transient ischemic attack in last 6 months
  • pacemaker, cardioverter-defibrillator or resynchronization device implanted less than 6 months before study entrance
  • severe chronic obstructive pulmonary disease
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01212705

Military Institute of Medicine
Warsaw, Szaserow 128, Poland, 04-141
Sponsors and Collaborators
Military Institute of Medicine, Poland
Principal Investigator: Anna Kazimierczak Military Institute of Medicine
  More Information

ClinicalTrials.gov Identifier: NCT01212705     History of Changes
Other Study ID Numbers: BW2126/10 
Study First Received: September 30, 2010
Last Updated: September 30, 2010

Additional relevant MeSH terms:
Heart Failure
Sleep Apnea, Central
Cheyne-Stokes Respiration
Heart Diseases
Cardiovascular Diseases
Sleep Apnea Syndromes
Respiration Disorders
Respiratory Tract Diseases
Sleep Disorders, Intrinsic
Sleep Wake Disorders
Nervous System Diseases
Signs and Symptoms, Respiratory
Signs and Symptoms

ClinicalTrials.gov processed this record on January 19, 2017