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Effect of Adaptive Servoventilation on Cardiac Function in Chronic Heart Failure and Cheyne-Stokes Respiration

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ClinicalTrials.gov Identifier: NCT01212705
Recruitment Status : Unknown
Verified September 2010 by Military Institute of Medicine, Poland.
Recruitment status was:  Recruiting
First Posted : October 1, 2010
Last Update Posted : October 1, 2010
Information provided by:

Study Description
Brief Summary:
Sleep disordered breathing is common in patients with chronic heart failure. Adaptive servoventilation is a novel method of treatment central sleep apnoea, especially associated with Cheyne-Stokes-respiration. The aim of the study is to investigate effect of adaptive servoventilation on cardiac function, exercise tolerance and quality of life in patients with chronic heart failure.

Condition or disease Intervention/treatment
Chronic Heart Failure Central Sleep Apnea Cheyne-Stokes Respiration Device: Adaptive servoventilation

Study Design

Study Type : Interventional  (Clinical Trial)
Official Title: Effect of Adaptive Servoventilation on Cardiac Function, Exercise Tolerance and Quality of Life in Patients With Chronic Heart Failure and Cheyne-Stokes Respiration

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Heart Failure
U.S. FDA Resources

Arms and Interventions

Arm Intervention/treatment
Experimental: ASV Device: Adaptive servoventilation
Background expiratory positive airway pressure with some inspiratory pressure support when needed

Outcome Measures

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All

Inclusion Criteria:

  • chronic heart failure with ejection fraction ≤45%
  • optimal medical treatment for at least 1 month
  • clinical diagnosis of Cheyne-Stokes respiration

Exclusion Criteria:

  • unstable heart failure
  • stroke
  • transient ischemic attack in last 6 months
  • pacemaker, cardioverter-defibrillator or resynchronization device implanted less than 6 months before study entrance
  • severe chronic obstructive pulmonary disease
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01212705

Contact: Anna Kazimierczak 48 22 6818017 annakazimierczak@poczta.onet.pl
Contact: Krystian Krzyzanowski 48 512 356 207 krystian.krzyzanowski@gmail.com

Military Institute of Medicine Recruiting
Warsaw, Szaserow 128, Poland, 04-141
Sponsors and Collaborators
Military Institute of Medicine, Poland
Principal Investigator: Anna Kazimierczak Military Institute of Medicine
More Information

ClinicalTrials.gov Identifier: NCT01212705     History of Changes
Other Study ID Numbers: BW2126/10
First Posted: October 1, 2010    Key Record Dates
Last Update Posted: October 1, 2010
Last Verified: September 2010

Additional relevant MeSH terms:
Heart Failure
Sleep Apnea, Central
Cheyne-Stokes Respiration
Heart Diseases
Cardiovascular Diseases
Sleep Apnea Syndromes
Respiration Disorders
Respiratory Tract Diseases
Sleep Disorders, Intrinsic
Sleep Wake Disorders
Nervous System Diseases
Signs and Symptoms, Respiratory
Signs and Symptoms