Physiological Brain Atlas Development

This study is currently recruiting participants. (see Contacts and Locations)
Verified June 2014 by Ohio State University
Information provided by (Responsible Party):
Ali Rezai, MD, Ohio State University Identifier:
First received: September 27, 2010
Last updated: June 26, 2014
Last verified: June 2014

Enrollment of candidates undergoing a deep brain stimulator (DBS) implant.

Condition Intervention
Parkinson Disease
Obsessive Compulsive Disorder
Other: No intervention

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Physiological Brain Atlas Development

Resource links provided by NLM:

Further study details as provided by Ohio State University:

Estimated Enrollment: 500
Study Start Date: August 2010
Estimated Study Completion Date: August 2015
Estimated Primary Completion Date: August 2014 (Final data collection date for primary outcome measure)
Intervention Details:
    Other: No intervention
    No intervention
    Other Name: Single Arm Group
Detailed Description:

The study proposes the enrollment of candidates undergoing a deep brain stimulator (DBS) implant. Data will be collected before, during and after surgery and will be electronically entered into the Atlas database where it will be stored indefinitely.

The purpose of the study is to create an Atlas to store physiological information utilizing non-rigid MRI normalization algorithms. In addition to collating and analyzing the physiological atlas in a statistical manner that allows the surgeon to predict optimal targeting locations for DBS implants based on multiple physiological variables, including pre-operative severity of disease, intraoperative neurophysiological observations, and post-operative response to DBS stimulation therapy.


Ages Eligible for Study:   7 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

All patients who are undergoing DBS implantation surgery at the Ohio State University.


Inclusion Criteria:

  • Any patient between the age of 7-90

Exclusion Criteria:

  • None
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01210534

Contact: Dina Aziz 6143666952

United States, Ohio
The Ohio Sate University Recruiting
Columbus, Ohio, United States, 43210
Contact: Dina Aziz    614-366-3623      
The Ohio State University Recruiting
Columbus, Ohio, United States, 43210
Contact: Dina Aziz    614-366-3623   
Sponsors and Collaborators
Ohio State University
Principal Investigator: Ali Rezai, MD Ohio State University
  More Information

No publications provided

Responsible Party: Ali Rezai, MD, MD, Ohio State University Identifier: NCT01210534     History of Changes
Other Study ID Numbers: 2010H0036
Study First Received: September 27, 2010
Last Updated: June 26, 2014
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Obsessive-Compulsive Disorder
Anxiety Disorders
Mental Disorders processed this record on March 26, 2015