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Study of Blood Samples From Patients With Ewing Sarcoma and Their Relatives

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ClinicalTrials.gov Identifier: NCT01210209
Recruitment Status : Unknown
Verified September 2010 by National Cancer Institute (NCI).
Recruitment status was:  Recruiting
First Posted : September 28, 2010
Last Update Posted : August 26, 2013
Sponsor:
Information provided by:
National Cancer Institute (NCI)

Brief Summary:

RATIONALE: Studying samples of blood in the laboratory from patients with cancer and their relatives may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.

PURPOSE: This research study is looking at blood samples collected from patients with Ewing sarcoma and their relatives.


Condition or disease Intervention/treatment
Sarcoma Other: genome-wide association study

Detailed Description:

OBJECTIVES:

  • To identify and characterize a genetic susceptibility factor to Ewing's sarcoma by performing a Genome-Wide Association Study with as many as possible Ewing sarcoma patients.

OUTLINE: This is a multicenter study.

Blood samples are collected from patients and their relatives. Blood DNA samples are analyzed for susceptibility genes of Ewing Sarcoma.


Study Type : Observational
Estimated Enrollment : 600 participants
Official Title: GENEWING - A Genome Wide Association Study in Ewing Sarcoma
Study Start Date : September 2009
Estimated Primary Completion Date : September 2011





Primary Outcome Measures :
  1. Identification and characterization of susceptibility genes in patients with Ewing sarcoma


Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

DISEASE CHARACTERISTICS:

  • Patients with Ewing sarcoma
  • Relatives of Ewing sarcoma patients

PATIENT CHARACTERISTICS:

  • Not specified

PRIOR CONCURRENT THERAPY:

  • Not specified

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01210209


Locations
France
Institut Curie Hopital Recruiting
Paris, France, 75005
Contact: Contact Person    33-1-5624-6679    olivier.delattre@curie.fr   
Sponsors and Collaborators
Institut Curie
Investigators
Principal Investigator: Olivier Delattre, MD Institut Curie

ClinicalTrials.gov Identifier: NCT01210209     History of Changes
Other Study ID Numbers: CDR0000683940
CLCC-IC-2009-02
2009-A00558-49
EU-21064
First Posted: September 28, 2010    Key Record Dates
Last Update Posted: August 26, 2013
Last Verified: September 2010

Keywords provided by National Cancer Institute (NCI):
Ewing sarcoma
Ewing sarcoma/peripheral primitive neuroectodermal tumor (PNET)

Additional relevant MeSH terms:
Sarcoma
Sarcoma, Ewing
Neoplasms, Connective and Soft Tissue
Neoplasms by Histologic Type
Neoplasms
Osteosarcoma
Neoplasms, Bone Tissue
Neoplasms, Connective Tissue