Spinal Cord Evoked Potentials as a Tool to Investigate Sensorimotor Processing (SCEPTISM)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01208805
Recruitment Status : Unknown
Verified September 2010 by Universitaire Ziekenhuizen Leuven.
Recruitment status was:  Not yet recruiting
First Posted : September 24, 2010
Last Update Posted : September 24, 2010
Information provided by:
Universitaire Ziekenhuizen Leuven

Brief Summary:

The study first aim is to investigate the relationship between different patterns of electrode stimulation and peripheral sensory stimulation and spinal cord-evoked potentials to optimize spinal cord stimulation parameters . The second aim of the study is to investigate the role of the spinal cord in some aspects of cognitive-sensory-motor processing, specifically the presence of top-down attentional effects on the sensory analysis of an external stimulus at the spinal cord level.

The study will be performed on patients that will be implanted with a spinal epidural electrode because of chronic intractable pain. From these electrodes, spinal cord evoked potentials (SCEPs) will be recorded.

Condition or disease Intervention/treatment
Studying Spinal Cord Evoked Potentials in Patients With Intractable Pain. Behavioral: Recording spinal cord evoked potentials

Study Type : Observational
Estimated Enrollment : 10 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Spinal Cord Evoked Potentials in Candidates for Dorsal Column Stimulation
Study Start Date : November 2010
Estimated Primary Completion Date : December 2011
Estimated Study Completion Date : July 2012

Group/Cohort Intervention/treatment
Candidates for dorsal column stimulation Behavioral: Recording spinal cord evoked potentials
Recording spinal cord evoked potentials from patients suffering from intractable pain in whom epidural electrodes have already been implanted

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 70 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with epidural elektrodes for intractable pain (spinal cord stimulation)

Inclusion Criteria:

  • Age: 18 - 70
  • Candidates for spinal cord stimulation
  • Epidural electrode at the the level of the cervical or thoracic spine.

Exclusion Criteria:

  • Generalized sensory deficit interfering with the recording of spinal cord evoked potentials

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01208805

Contact: Tom Theys, MD +32 16 344290
Contact: Bart Nuttin, MD PhD +32 16 344290

UZ Leuven Not yet recruiting
Leuven, Brabant, Belgium, 3000
Contact: An Hendriks    +32 16 34 19 98   
Principal Investigator: Bart Nuttin, MD PhD         
Sponsors and Collaborators
Universitaire Ziekenhuizen Leuven

Responsible Party: Prof Bart Nuttin, UZ Leuven Identifier: NCT01208805     History of Changes
Other Study ID Numbers: S52573
First Posted: September 24, 2010    Key Record Dates
Last Update Posted: September 24, 2010
Last Verified: September 2010

Additional relevant MeSH terms:
Pain, Intractable
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms