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The Psychological Treatment of Overweight Binge Eaters Minority Supplement

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01208259
First Posted: September 23, 2010
Last Update Posted: September 28, 2010
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Washington University School of Medicine
  Purpose
Cognitive-behavioral therapy (CBT) has documented efficacy for the treatment of binge eating disorder (BED). Interpersonal psychotherapy (IPT) has been shown to reduce binge eating but its long-term impact and time course on other BED-related symptoms remain largely unknown. This study compares the effects of group CBT and group IPT across BED-related symptoms among overweight individuals with BED.

Condition Intervention Phase
Binge Eating Disorder Cognitive Therapy/Methods Mental Disorders/Epidemiology Obesity/Epidemiology Obesity/Therapy Behavioral: Cognitive Behavioral Therapy (CBT) Behavioral: Interpersonal Therapy (IPT) Phase 1 Phase 2

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Treatment
Official Title: A Randomized Comparison of Group-Behavioral Therapy and Group Interpersonal Psychotherapy for the Treatment of Overweight Individuals With Binge-Eating Disorder Minority Supplement

Resource links provided by NLM:


Further study details as provided by Washington University School of Medicine:

Primary Outcome Measures:
  • Short and long-term efficacy of two treatments for binge eating among the overweight: Group Cognitive-Behavior (CBT) and Group Interpersonal Therapy (IPT).
    Assessments of binge eating and associated eating disorder psychopathology, general psychological functioning, and weight occurred before treatment, at post treatment, and at 4-month intervals up to 12 months following treatment.


Enrollment: 162
Study Start Date: April 1997
Study Completion Date: March 1999
Primary Completion Date: March 1999 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Binge Eating Disorder/Therapy Behavioral: Cognitive Behavioral Therapy (CBT) Behavioral: Interpersonal Therapy (IPT)

Detailed Description:
Cognitive-behavioral therapy (CBT) has documented efficacy for the treatment of binge eating disorder (BED). Interpersonal psychotherapy (IPT) has been shown to reduce binge eating but its long-term impact and time course on other BED-related symptoms remain largely unknown. This study compares the effects of group CBT and group IPT across BED-related symptoms among overweight individuals with BED. METHODS: One hundred sixty-two overweight patients meeting DSM-IV criteria for BED were randomly assigned to 20 weekly sessions of either group CBT or group IPT. Assessments of binge eating and associated eating disorder psychopathology, general psychological functioning, and weight occurred before treatment, at posttreatment, and at 4-month intervals up to 12 months following treatment. RESULTS: Binge-eating recovery rates were equivalent for CBT and IPT at posttreatment (64 [79%] of 81 vs 59 [73%] of 81) and at 1-year follow-up (48 [59%] of 81 vs 50 [62%] of 81). Binge eating increased slightly through follow-up but remained significantly below pretreatment levels. Across treatments, patients had similar significant reductions in associated eating disorders and psychiatric symptoms and maintenance of gains through follow-up. Dietary restraint decreased more quickly in CBT but IPT had equivalent levels by later follow-ups. Patients' relative weight decreased significantly but only slightly, with the greatest reduction among patients sustaining recovery from binge eating from posttreatment to 1-year follow-up. CONCLUSIONS: Group IPT is a viable alternative to group CBT for the treatment of overweight patients with BED. Although lacking a nonspecific control condition limits conclusions about treatment specificity, both treatments showed initial and long-term efficacy for the core and related symptoms of BED.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • DSM-IV research criteria for binge-eating disorder
  • Average of greater than or equal to 2 days of binge eating per week for at least 6 months' duration
  • Marked stress regarding binge eating
  • At least 3 to 5 associated behavioral features (e.g. eating when not physically hungry) Other study criteria
  • 18-65 years old
  • Body mass index, 27-48 kg/m squared

Exclusion Criteria:

  • Pregnant or planning to become pregnant
  • Taking weight-affecting or psychotropic medications
  • Psychiatric conditions warranting immediate treatment
  • Current enrollment in psychotherapy or a weight loss program
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01208259


Locations
United States, Connecticut
Yale University
New Haven, Connecticut, United States, 06511-3516
Sponsors and Collaborators
Washington University School of Medicine
Investigators
Principal Investigator: Denise E Wilfley, Ph.D. Washington University School of Medicine
  More Information

Publications:
Responsible Party: Denise E. Wilfley, Ph.D., San Diego State University
ClinicalTrials.gov Identifier: NCT01208259     History of Changes
Other Study ID Numbers: R29MH138403
First Submitted: August 31, 2010
First Posted: September 23, 2010
Last Update Posted: September 28, 2010
Last Verified: September 2010

Keywords provided by Washington University School of Medicine:
Body Mass Index
Bulimia/therapy
Comorbidity
Interpersonal Relations
Psychotherapy/methods

Additional relevant MeSH terms:
Disease
Obesity
Overweight
Feeding and Eating Disorders
Mental Disorders
Psychotic Disorders
Bulimia
Binge-Eating Disorder
Pathologic Processes
Overnutrition
Nutrition Disorders
Body Weight
Signs and Symptoms
Schizophrenia Spectrum and Other Psychotic Disorders
Hyperphagia
Signs and Symptoms, Digestive