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Immunological Changes Through Narrative Treatment of Post-Traumatic Stress Disorder (PTSD) in Torture Victims

This study has been completed.
German Research Foundation
Information provided by (Responsible Party):
Iris-Tatjana Kolassa, University of Ulm Identifier:
First received: September 21, 2010
Last updated: February 21, 2012
Last verified: February 2012
Posttraumatic stress disorder (PTSD) is associated with poor health, high health care utilization, and an increased risk for a variety of somatic, inflammatory and autoimmune diseases. Research, including our own findings, indicates immunological alterations in PTSD patients. The aim of this study is to investigate whether alterations in the immune system of PTSD patients are reversible through a trauma-specific short-term therapy (Narrative Exposure Therapy).

Condition Intervention
Behavioral: NET

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Immunological Changes Through Narrative Treatment of PTSD in Torture Victims

Resource links provided by NLM:

Further study details as provided by University of Konstanz:

Primary Outcome Measures:
  • PTSD diagnosis and severity score according to the Clinicians Administered PTSD Scale (CAPS) [ Time Frame: 4 month after completion of treatment ]

Secondary Outcome Measures:
  • changes in immunological parameters [ Time Frame: 4 months after completion of treatment ]

Enrollment: 47
Study Start Date: June 2009
Study Completion Date: January 2012
Primary Completion Date: May 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Narrative Exposure Therapy (NET) Behavioral: NET
Narrative Exposure Therapy for traumatized survivors of organized violence
No Intervention: Waitinglist Control Group


Ages Eligible for Study:   16 Years to 60 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • PTSD diagnosis
  • experiences of organized violence/torture

Exclusion Criteria:

  • psychotic disorder
  • chronic inflammatory diseases
  Contacts and Locations
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Please refer to this study by its identifier: NCT01206790

University of Konstanz, Department of Psychology
Konstanz, Germany, 78467
Sponsors and Collaborators
University of Konstanz
German Research Foundation
Principal Investigator: Iris-Tatjana Kolassa, Prof. Dr. University of Ulm
  More Information

Responsible Party: Iris-Tatjana Kolassa, Prof. Dr. Iris-Tatjana Kolassa, University of Ulm Identifier: NCT01206790     History of Changes
Other Study ID Numbers: NET-2010-KN
Study First Received: September 21, 2010
Last Updated: February 21, 2012

Keywords provided by University of Konstanz:
Narrative Exposure Therapy
torture victims
immune system

Additional relevant MeSH terms:
Stress Disorders, Post-Traumatic
Stress Disorders, Traumatic
Trauma and Stressor Related Disorders
Mental Disorders processed this record on May 23, 2017