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Macrophagic Activation and Immunophenotypic Profile of Patients With Gaucher's Disease (Gaucher)

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01206673
First Posted: September 22, 2010
Last Update Posted: December 2, 2011
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Nantes University Hospital
  Purpose
The aim of this study is to evaluate macrophaging activity and immunologic profile of patients with Gaucher 's disease. For this, one blood sampling will be performed.

Condition Intervention
Patients With Gaucher's Disease Other: Blood sampling

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Basic Science
Official Title: Evaluation of Macrophagic Activation and Immunophenotypic Profile of Patients With Gaucher's Disease.

Resource links provided by NLM:


Further study details as provided by Nantes University Hospital:

Primary Outcome Measures:
  • To determine the implication of acquired and inherent immunity in the Gaucher's clinical phenotype at moment of blood sampling

Secondary Outcome Measures:
  • to find new activity mark for Gaucher's disease by studying macrophagic activation's markers.

Enrollment: 10
Study Start Date: December 2009
Study Completion Date: July 2011
Primary Completion Date: July 2011 (Final data collection date for primary outcome measure)
Intervention Details:
    Other: Blood sampling
    One blood sampling is required for the research
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Adults (age equal or above 18.
  • Patients with Gaucher 's disease treated in the "Grand Ouest" competence center
  • patients affiliated to social security
  • Informed consent signed

Exclusion Criteria:

- Children (age<18)

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01206673


Locations
France
Nantes Hospital
Nantes, France, 44093
CHU of Rennes
Rennes, France, 35
Sponsors and Collaborators
Nantes University Hospital
  More Information

Responsible Party: Nantes University Hospital
ClinicalTrials.gov Identifier: NCT01206673     History of Changes
Other Study ID Numbers: 09/07-I
First Submitted: September 21, 2010
First Posted: September 22, 2010
Last Update Posted: December 2, 2011
Last Verified: December 2011

Additional relevant MeSH terms:
Gaucher Disease
Sphingolipidoses
Lysosomal Storage Diseases, Nervous System
Brain Diseases, Metabolic, Inborn
Brain Diseases, Metabolic
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Metabolism, Inborn Errors
Genetic Diseases, Inborn
Lipidoses
Lipid Metabolism, Inborn Errors
Lysosomal Storage Diseases
Metabolic Diseases
Lipid Metabolism Disorders