Metformin for Treatment Antipsychotic Induced Amenorrhea in Female Schizophrenic Patients
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ClinicalTrials.gov Identifier: NCT01206153 |
Recruitment Status
:
Completed
First Posted
: September 21, 2010
Last Update Posted
: September 21, 2010
|
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Amenorrhea | Drug: metformin | Phase 4 |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 84 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) |
Official Title: | Metformin for Treatment Antipsychotic Induced Amenorrhea in Female Schizophrenic Patients: a Double Blind, Placebo-controlled Study |
Study Start Date : | June 2008 |
Actual Primary Completion Date : | January 2010 |
Actual Study Completion Date : | March 2010 |
Arm | Intervention/treatment |
---|---|
Experimental: metformin | Drug: metformin |
- prolactin levelthe outcome measure assess a efficacy.
- fasting glucose

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Ages Eligible for Study: | 18 Years to 40 Years (Adult) |
Sexes Eligible for Study: | Female |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- schizophrenia patient
- amenorrhea for more than three months after antipsychotic treatment
Exclusion Criteria:
- liver or renal diseases
- pregnant or lactating women
- cardiovascular diseases
- hypertension or diabetes mellitus

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01206153
China, Hunan | |
Institute of Mental Health of The Second Xiangya Hospital, Central South University | |
Changsha, Hunan, China, 410011 |
Principal Investigator: | Jingping Zhao, MD | Institute of Mental Health of The Second Xiangya Hospital, Central South University, 139# Renmin Middle Road,Changsha 410011, Hunan, P.R. China |
Responsible Party: | Jingping Zhao, the Second Xiangya Hospital of Central South University |
ClinicalTrials.gov Identifier: | NCT01206153 History of Changes |
Other Study ID Numbers: |
RWu |
First Posted: | September 21, 2010 Key Record Dates |
Last Update Posted: | September 21, 2010 |
Last Verified: | February 2008 |
Additional relevant MeSH terms:
Amenorrhea Menstruation Disturbances Pathologic Processes Metformin Antipsychotic Agents |
Hypoglycemic Agents Physiological Effects of Drugs Tranquilizing Agents Central Nervous System Depressants Psychotropic Drugs |