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Testing the Effectiveness of a Computer-based Program for Depression

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01203683
First Posted: September 16, 2010
Last Update Posted: October 10, 2013
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
University of Texas at Austin
  Purpose
The purpose of this study is to determine whether completing a computer-based program alters changes how the brain processes emotional information and improves symptoms of depression.

Condition Intervention Phase
Major Depressive Disorder Behavioral: Active computer-based training Behavioral: Inert computer training Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Attention Training for Major Depressive Disorder

Further study details as provided by University of Texas at Austin:

Primary Outcome Measures:
  • Beck Depression Inventory-II [ Time Frame: Week 4, Week 9 ]
    Questionnaire to assess depression symptom severity


Secondary Outcome Measures:
  • Structured Clinical Interview for DSM-IV diagnoses [ Time Frame: Week 9 ]
    Diagnostic interview to assess for presence of Major depressive disorder (MDD).

  • Neural processing of emotion stimuli [ Time Frame: Week 4 ]
    fMRI paradigm to assess neural changes in how individuals processes emotional stimuli


Enrollment: 53
Study Start Date: January 2011
Study Completion Date: October 2013
Primary Completion Date: October 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Active Computer-Based Program
Putatively therapeutic computer program.
Behavioral: Active computer-based training
8 sessions across 4 weeks.
Placebo Comparator: Placebo computer-based program
Inert computer program.
Behavioral: Inert computer training
8 sessions across 4 weeks.

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 55 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Major Depressive Disorder

Exclusion Criteria:

  • Substance dependence, psychotic disorder, bipolar disorder, schizophrenia, current psychotherapy, medications other than selective serotonin reuptake inhibitors
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01203683


Locations
United States, Texas
University of Texas at Austin
Austin, Texas, United States, 78712
Sponsors and Collaborators
University of Texas at Austin
Investigators
Principal Investigator: Christopher Beevers, PhD University of Texas at Austin
  More Information

Responsible Party: University of Texas at Austin
ClinicalTrials.gov Identifier: NCT01203683     History of Changes
Other Study ID Numbers: 2010-09-0004
First Submitted: September 15, 2010
First Posted: September 16, 2010
Last Update Posted: October 10, 2013
Last Verified: October 2013

Keywords provided by University of Texas at Austin:
depression

Additional relevant MeSH terms:
Depressive Disorder
Depression
Depressive Disorder, Major
Mood Disorders
Mental Disorders
Behavioral Symptoms